Abstract
Castleman’s disease (CD) is an uncommon lymphoproliferative disorder. Its etiology is related to HHV-8 infection, with immunocompromised patients as the most vulnerable population. Patients with the multicentric variant of CD require systemic treatment but the disease course often includes severe complications or evolution into malignant neoplasm. PET with 18F-FDG is useful in the early detection of metabolically active CD lesions, in assessing disease extent, guiding biopsy, discriminating disease persistence/recurrence from post-therapeutic changes, and monitoring the response to treatment. The value of PET/CT in the differential diagnosis between CD and malignancies such as lymphoma requires further study.
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© 2014 Springer-Verlag Italia
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Cucinotta, M., Cistaro, A. (2014). Castleman’s Disease. In: Cistaro, A. (eds) Atlas of PET/CT in Pediatric Patients. Springer, Milano. https://doi.org/10.1007/978-88-470-5358-8_33
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DOI: https://doi.org/10.1007/978-88-470-5358-8_33
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