Abstract
Adverse Drug Events (ADEs) are commonly differentiated in two classes: Type A, as predictable reactions related to the pharmacological properties of the drug in study; Type B, as unpredictable events in predisposed individuals. The former group includes side effects, toxicity of overdose, secondary effects, and drug interactions. Overall, they contribute for about 80–90 % of ADEs. The latter group includes hypersensitivity (immunological) reactions, and non-specific reactions, such as pseudo-allergic (anaphylactoid) reactions and idiosyncrasy, all contributing for the remaining 10–20 % of events [1, 2].
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Tridente, G. (2014). Adverse Drug Events to Biomedicines. In: Adverse Events with Biomedicines. Springer, Milano. https://doi.org/10.1007/978-88-470-5313-7_2
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DOI: https://doi.org/10.1007/978-88-470-5313-7_2
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