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Tumors of the Chest Wall

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Book cover Pediatric Thoracic Surgery

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Abstract

Chest wall tumors (CWTs) in children comprise a wide range of benign and malignant neoplasms. These tumors are rare in infants, children and young adults, accounting for 1.8% of solid tumors [1]. However, high proportions of CWTs are malignant, and represent a diagnostic and therapeutic challenge to pediatric thoracic surgeons. The chest wall can be affected by: primary malignant neoplasms arising from different structures; secondary tumors which can invade the chest wall from the adjacent structures (e.g., breast, pleura, mediastinum, lung); metastatic tumors [2].

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References

  1. Shamberger RC, Grier HE (1994) Chest wall tumors in infants and children. Semin Pediatr Surg 3:267–76

    PubMed  CAS  Google Scholar 

  2. Dang NC, Siegel SE, Phillips JD (1999) Malignant chest wall tumors in children and young adults. J Pediatr Surg 34:1773–1778

    Article  PubMed  CAS  Google Scholar 

  3. Saenz NC, Hass DJ, Meyers P et al (2000) Pediatric chest wall Ewing’s sarcoma. J Pediatr Surg 35:550–555

    Google Scholar 

  4. Boyacigil S, Damgaci L, Duran S, Yavuz SO (2003) Primitive neuroectodermal tumor of the chest wall (Askin tumor). Tani Girisim Radyol 9:108–109

    PubMed  Google Scholar 

  5. Shamberger RC, Tarbell NJ, Perez-Atayde AR, Grier HE (1994) Malignant small round cell tumor (Ewing’s-PNET) of the chest wall in children. J Pediatr Surg 29:179–184

    Article  PubMed  CAS  Google Scholar 

  6. Athanassiadi K, Kalavrouziotis G, Rondogianni D et al (2001) Primary chest wall tumors: early and long-term results of surgical treatment. Eur J Cardiothorac Surg 19:589–593

    Google Scholar 

  7. Levesque J, Marx R, Bell RS et al (1998) A clinical guide to primary bone tumors. Baltimore (MD): Williams & Williams

    Google Scholar 

  8. Tateishi U, Gladish GW, Kusumoto M et al (2003) Chest wall tumors: radiologic findings and pathologic correlation: part 1. Benign tumors. Radiographics 23:1477–1490

    Google Scholar 

  9. La Quaglia MP (2008) Chest wall tumors in childhood and adolescence. Semin Pediatr Surg 17:173–180

    Article  PubMed  Google Scholar 

  10. Mortman KD, Hochheiser GM, Giblin EM et al (2007) Elastofibroma dorsi: clinicopathologic review of 6 cases. Ann Thorac Surg 83:1894–1897

    Google Scholar 

  11. Coffin CM, Dehner LP (1991) Fibroblastic-myofibroblastic tumors in children and adolescents: a clinicopathologic study of 103 patients. Pediatr Pathol 11:559–588

    Article  Google Scholar 

  12. Chung EB, Enzinger FM (1981) Infantile myofibromatosis. Cancer 48:1807–1818

    Article  PubMed  CAS  Google Scholar 

  13. Wiswell TE, Davis J, Cunningham BE, Solenberger R, Thomas PJ (1988) Infantile myofibromatosis: the most common fibrous tumor J Pediatr Surg 23:315–318

    Article  PubMed  CAS  Google Scholar 

  14. Briselli MF, Soule EH, Gilchrist GS (1980) Congenital fibromatosis: report of 18 cases of solitary and 4 cases of multiple tumors. Mayo Clin Proc 55:554–562

    PubMed  CAS  Google Scholar 

  15. Enzinger FM, Weiss SW (1988) Soft tissue tumors (second edn) St Louis, Mosby

    Google Scholar 

  16. Abbas AE, Deschamps C, Cassivi S D et al (2004) Chest wall desmoid tumors: results of surgical intervention. Ann Thorac Surg 78:1219–1223

    Google Scholar 

  17. van den Berg H, van Rijn RR, Merks JH (2008) Management of tumors of the chest wall in childhood: a review. J Pediatr Hematol Oncol 30:214–221

    Article  PubMed  Google Scholar 

  18. Hayry P, Scheinin TM (1988) The desmoid (Reitamo) syndrome: etiology, manifestations, pathogenesis, and treatment. Curr Probl Surg 25:225–320

    PubMed  CAS  Google Scholar 

  19. Leonhardt J, Schirg E, Schmidt H, Gluer S (2004) Imaging characteristics of childhood lipoblastoma. Röfo 176: 972–975

    PubMed  CAS  Google Scholar 

  20. Abel RM, Bryan RT, Rafaat F, Haigh F, Sethia B, Parikh D (2003) Axillary lipoblastoma-tumor recurrence in the right atrium. J Pediatr Surg 38:1246–1247

    Article  PubMed  CAS  Google Scholar 

  21. Bastian BC, Harms D, Kreipe HH, Hamm H, Brocker EB (1996) Giant cell fibroblastoma. A rare soft tissue tumor in childhood. Hautarzt 47:299–303

    Article  PubMed  CAS  Google Scholar 

  22. Fong YC, Pairolero PC, Sim FH, Cha SS, Blanchard CL, Scully SP (2004) Chondrosarcoma of the chest wall: a retrospective clinical analysis. Clin Orthop Relat Res 427:184–189

    Article  PubMed  Google Scholar 

  23. Burt M, Fulton M, Wessner-Dunlap S et al (1992) Primary bony and cartilaginous sarcomas of chest wall: results of therapy. Ann Thorac Surg 54:226–232

    Google Scholar 

  24. Hsu PK, Hsu HS, Lee HC et al (2006) Management of primary chest wall tumors: 14 years’ clinical experience. J Chin Med Assoc 69:377–382

    Google Scholar 

  25. Wong KS, Hung IJ, Wang CR, Lien R (2004) Thoracic wall lesions in children. Pediatr Pulmonol 37:257–263

    Article  PubMed  Google Scholar 

  26. Dorfman HD, Czerniak B (eds) (1998) Bone tumors. Mosby, St Louis, Yearbook, p 253–350

    Google Scholar 

  27. Mirra JM (1989) Bone tumors: clinical, radiologic and pathologic correlations. Lea and Febiger, Philadelphia, p 439–535

    Google Scholar 

  28. Brien EW, Mirra JM, Kerr R (1997) Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. I. The intramedullary cartilage tumors. Skeletal Radiol 26:325–353

    Article  PubMed  CAS  Google Scholar 

  29. Engelmann C, Stanulla H (1972) Diagnosis and therapy of primary chest wall tumors. Zentralbl Chir 97:905–920

    PubMed  CAS  Google Scholar 

  30. Barei DP, Moreau G, Scarborough MT, Neel MD (1999) Percutaneous radiofrequency thermal ablation of osteoid osteoma. Operative Tech Orthop 9:72–78

    Article  Google Scholar 

  31. Cavanaugh DG, Cabellon S, Jr, Peake JB (1986) A logical approach to chest wall neoplasms. Ann Thorac Surg 41:436–437

    Article  PubMed  CAS  Google Scholar 

  32. Berard J, Jaubert de Beaujeu M, Valla JS (1982) Primary tumors of the ribs in children and adolescents. Apropos of 15 cases. Chir Pediatr 23:387–392

    PubMed  CAS  Google Scholar 

  33. Benz G, Schafer K, Daum R. (1990) Tumors of the ribs in children. Chir Pediatr 31:152–156

    PubMed  CAS  Google Scholar 

  34. Ayala AG, Ro JY, Bolio-Solis A (1993) Mesenchymal hamartoma of the chest wall in infants and children: A clinicopathological study of five patients. Skeletal Radiol 22:569–576

    Article  PubMed  CAS  Google Scholar 

  35. Groom KR, Murphey MD, Howard LM et al (2002) Mesenchymal hamartoma of the chest wall: Radiologic manifestations with emphasis on cross-sectional imaging and histopathologic comparison. Radiology 222:205–211

    Google Scholar 

  36. Shimotake T, Fumino S, Aoi S et al (2005) Respiratory insufficiency in a newborn with mesenchymal hamartoma of the chest wall occupying the thoracic cavity. J Pediatr Surg 40:E13–E16

    Google Scholar 

  37. Jung AL, Johnson DG, Condon VR et al (1994) Congenital chest wall mesenchymal hamartoma. J Perinatol 14:487–491

    Google Scholar 

  38. Okada A, Takahashi S, Tanimizu T et al (2005) Chest wall mesenchymal harmartoma associated with a massive fetal pleural effusion: A case report. J Pediatr Surg 40:e5–e7

    Google Scholar 

  39. Freeburn AM, McAloon J (2001) Infantile chest hamartoma-case outcome aged 11. Arch Dis Child 85:244–245

    Article  PubMed  CAS  Google Scholar 

  40. Askin FB, Rosai J, Sibley RK et al (1979) Malignant small cell tumor of the thoracopulmonary region in childhood: a distinctive clinicopathologic entity of uncertain histogenesis. Cancer 43:2438–2451

    Google Scholar 

  41. Dehner LP. (1986) Peripheral and central primitive neuroectodermal tumors. A nosologic concept seeking a consensus. Arch Pathol Lab Med 110:997–1005

    PubMed  CAS  Google Scholar 

  42. Sasou S, Nakamura SI, Habano W, Takano T (1996) True malignant histiocytosis developed during chemotherapy for mediastinal immature teratoma. Hum Pathol 27:1099–1103

    Article  PubMed  CAS  Google Scholar 

  43. Winer-Muram HT, Kauffman WM, Gronemeyer SA, Jennings SG. Primitive neuroectodermal tumors of the chest wall (Askin tumors): CT and MR findings. Am J Roentgenol 1993;vn]:265–268

    Google Scholar 

  44. Whang-Peng J, Triche TJ, Knutsen T et al (1986) Cytogenetic characterization of selected small round cell tumors of childhood. Cancer Genet Cytogenet 21:185–208

    Google Scholar 

  45. Shamberger RC, Laquaglia MP, Krailo MD et al (2000) Ewing sarcoma of the rib: results of an intergroup study with analysis of outcome by timing of resection. J Thorac Cardiovasc Surg 119:1154–1161

    Google Scholar 

  46. Arai Y, Kun LE, Brooks MT, Fairclough DL et al (1991) Ewing’s sarcoma: local tumor control and patterns of failure following limited-volume radiation therapy. Int J Radiat Oncol Biol Phys 21:1501–1518

    Google Scholar 

  47. Sherman NE, Romsdahl M, Evans H, Zagars G, Oswald MJ (1990) Desmoid tumors: a 20-year radiotherapy experience. Int J Radiat Oncol Biol Phys 19:37–40

    Article  PubMed  CAS  Google Scholar 

  48. McKinnon JG, Neifeld JP, Kay S et al (1989) Management of desmoid tumors. Surg Gynecol Obstet 169:104–116

    Google Scholar 

  49. Maurer HM, Gehan EA, Beltangady M et al (1993) The Intergroup Rhabdomyosarcoma Study-II. Cancer 71:1904–1922

    Google Scholar 

  50. Maurer HM, Beltangady M, Gehan EA et al (1988) The Intergroup Rhabdomyosarcoma Study-I. A final report. Cancer 61:209–220

    Google Scholar 

  51. Crist WM, Raney RB Jr, Newton W (1982) Intrathoracic soft tissue sarcomas in children. Cancer 50:598–604

    Article  PubMed  CAS  Google Scholar 

  52. Young MM, Kinsella TJ, Miser JS et al (1989) Treatment of the sarcomas of the chest wall using intensive combined modality therapy. Int J Radiat Oncol Biol Phys 16:49–57

    Google Scholar 

  53. Raney RB (1984) Localized sarcoma of the chest wall. Med Pediatr Oncol 12:116–118

    Article  PubMed  Google Scholar 

  54. Chung A, Enzinger FM (1981) Infantile myofibromatosis. Cancer 48:1807–1818

    Article  PubMed  CAS  Google Scholar 

  55. Grosfeld JL, Rescorla FJ, West KW et al (1998) Chest wall resection and reconstruction for malignant conditions in childhood. J Pediatr Surg 23:667–673

    Google Scholar 

  56. Arnold PG, Pairolero PC (1996) Chest-wall reconstruction: an account of 500 consecutive patients. Plast Reconstr Surg 98:804–810

    Article  PubMed  CAS  Google Scholar 

  57. Carachi R, Audry G, Ranke A, Azmy A, Bilweis J, Gruner M. (1995) Collagen-coated Vicryl mesh: a new bioprosthesis in pediatric surgical practice. J Pediatr Surg 30:1302–1305

    Article  PubMed  CAS  Google Scholar 

  58. Stocker J (2001) The respiratory tract. In: Stocker J, Dehner L (eds) Pediatric pathology. Lippincott, Williams and Wilkins, Philadelphia, p 445–517

    Google Scholar 

  59. Tucker MA, D’Angio GJ, Boice JD Jr et al (1987) Bone sarcomas linked to radiotherapy and chemotherapy in children. N Engl J Med 317:588–593

    Google Scholar 

  60. Strong LC, Herson J, Osborne BM, Sutow WW (1979) Risk of radiation-related subsequent malignant tumors in survivors of Ewing’s sarcoma. J Natl Cancer Inst 62:1401–1406

    PubMed  CAS  Google Scholar 

  61. Kuttesch JF Jr, Wexler LH, Marcus RB et al (1996) Second malignancies after Ewing’s sarcoma: radiation dose-dependency of secondary sarcomas. J Clin Oncol 14:2818–2825

    Google Scholar 

  62. Paulussen M, Ahrens S, Lehnert M et al (2001) Second malignancies after Ewing tumor treatment in 690 patients from a cooperative German/Austrian/Dutch study. Ann Oncol 12:1619–1630

    Google Scholar 

  63. Young MM, Kinsella TJ, Miser JS et al (1989) Treatment of sarcomas of the chest wall using intensive combined modality therapy. Int J Radiat Oncol Biol Phys 16:49–57

    Article  PubMed  CAS  Google Scholar 

  64. Ozaki T, Lindner N, Hoffmann C et al(1995) Ewing’s sarcoma of the ribs. A report from the cooperative Ewing’s sarcoma study. Eur J Cancer 31A (13–14):2284–2288

    Google Scholar 

  65. Lans TE, van der Pol C, Wouters MW et al. (2009) Complications in wound healing after chest wall resection in cancer patients; a multivariate analysis of 220 patients. J Thorac Oncol 4:639–643

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Pediatric Oncology and Hematology, Policlinico S. Orsola-Malpighi University of Bologna, Bologna, Italy

    Andrea Pession

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  1. Riccardo Masetti
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  2. Daniele Zama
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  3. Luca Bertelli
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  4. Tamara Belotti
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  5. Andrea Pession
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Correspondence to Andrea Pession .

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  1. Pediatric Surgery, University of Bologna, Bologna, Italy

    Mario Lima

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Masetti, R., Zama, D., Bertelli, L., Belotti, T., Pession, A. (2013). Tumors of the Chest Wall. In: Lima, M. (eds) Pediatric Thoracic Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-5202-4_37

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  • DOI: https://doi.org/10.1007/978-88-470-5202-4_37

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-5201-7

  • Online ISBN: 978-88-470-5202-4

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