Skip to main content
SpringerLink
Log in
Book cover

Ulcerative Colitis pp 173–194Cite as

Long-term Complications after Surgical Treatment of Ulcerative Colitis

  • Chapter

  • 1293 Accesses

Part of the book series: Updates in Surgery ((UPDATESSURG))

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Hurst RD, Molinari M, Chung TP et al (1996) Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy. Arch Surg 131(5):497–500

    Article  CAS  Google Scholar 

  2. Meagher AP, Farouk R, Dozois RR et al (1998) J ileal pouch-anal anastomosis for chronic ulcerative colitis: complications and long-term outcome in 1310 patients. Br J Surg 85(6):800–803

    Article  CAS  Google Scholar 

  3. Penna C, Dozois R, Tremaine W et al (1996) Pouchitis after ileal pouch-anal anastomosis for ulcerative colitis occurs with increased frequency in patients with associated primary sclerosing cholangitis. Gut 38(2):234–239

    Article  CAS  Google Scholar 

  4. Landy J, Al-Hassi HO, McLaughlin SD et al (2012) Etiology of pouchitis. Inflamm Bowel Dis 18(6):1146–1155

    Article  CAS  Google Scholar 

  5. Carter MJ, Di Giovine FS, Cox A et al (2001) The interleukin 1 receptor antagonist gene allele 2 as a predictor of pouchitis following colectomy and IPAA in ulcerative colitis. Gastroenterology 121(4):805–811

    Article  CAS  Google Scholar 

  6. Meier CB, Hegazi RA, Aisenberg J et al (2005) Innate immune receptor genetic polymorphisms in pouchitis: is CARD15 susceptibility factor? Inflamm Bowel Dis 11(11):965–971

    Article  Google Scholar 

  7. Achkar JP, Al-Haddad M, Lashner B et al (2005) Differentiating risk factors for acute and chronic pouchitis. Clin Gastroenterol Hepatol 3(1):60–66

    Article  Google Scholar 

  8. Fleshner P, Ippoliti A, Dubinsky M et al (2007) A prospective multivariate analysis of clinical factors associated with pouchitis after ileal pouch-anal anastomosis. Clin Gastroenterol Hepatol 5(8):952–958

    Article  Google Scholar 

  9. Sandborn WJ, Tremaine WJ, Batts KP et al (1994) Pouchitis after ileal pouch-anal anastomosis: a Pouchitis Disease Activity Index. Mayo Clin Proc 69(5):409–415

    Article  CAS  Google Scholar 

  10. Shen B, Achkar J-P, Lashner BA et al (2001) Endoscopic and histologic evaluation together with symptom assessment are required to diagnose pouchitis. Gastroenterology 121(2):261–267

    Article  CAS  Google Scholar 

  11. Shen B, Achkar JP, Connor JT et al (2003) Modified pouchitis disease activity index: a simplified approach to the diagnosis of pouchitis. Dis Colon Rectum 46(6):748–753

    Article  Google Scholar 

  12. Sandborn WJ (1996) Pouchitis: risk factors, frequency, natural history, classification and public health prospective. In: McLeod RS, Martin F, Sutherland LR et al (eds) Trends in inflammatory bowel disease therapy. Kluwer Academic Publishers, Dordrecht

    Google Scholar 

  13. Shen B, Remzi FH, Lavery IC et al (2008) A proposed classification of ileal pouch disorders and associated complications after restorative proctocolectomy. Clin Gastroenterol Hepatol 6(2):145–158

    Article  Google Scholar 

  14. Pardi DS, D’Haens G, Shen B et al (2009) Clinical guidelines for the management of pouchitis. Inflamm Bowel Dis 15(9):1424–1431

    Article  Google Scholar 

  15. Fazio VW, Kiran RP, Remzi FH et al (2013) Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients. Ann Surg 257(4):679–685

    Article  Google Scholar 

  16. Sandborn W, McLeod R, Jewell D (2000) Pharmacotherapy for inducing and maintaining remission in pouchitis. Cochrane Database Syst Rev 2000(2):CD001176

    Google Scholar 

  17. Shen B, Achkar JP, Lashner BA et al (2001) A randomized clinical trial of ciprofloxacin and metronidazole to treat acute pouchitis. Inflamm Bowel Dis 7(4):301–305

    Article  CAS  Google Scholar 

  18. Mimura T, Rizzello F, Helwig U et al (2004) Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut 53(1): 108–114

    Article  CAS  Google Scholar 

  19. Gionchetti P, Rizzello F, Venturi A et al (2000) Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 119(2):305–309

    Article  CAS  Google Scholar 

  20. Singh S, Stroud AM, Holubar SD et al (2015) Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis. Cochrane Database Syst Rev 2015(11):CD001176

    Google Scholar 

  21. Sartor RB (2000) Probiotics in chronic pouchitis: restoring luminal microbial balance. Gastroenterology 119(2):584–587

    Article  CAS  Google Scholar 

  22. Gionchetti P, Rizzello F, Helwig U et al (2003) Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology 124(5):1202–1209

    Article  Google Scholar 

  23. Gionchetti P, Rizzello F, Poggioli G et al (2007) Oral budesonide in the treatment of chronic refractory pouchitis. Aliment Pharmacol Ther 25(10):1231–1236

    Article  CAS  Google Scholar 

  24. Gionchetti P, Rizzello F, Venturi A et al (1999) Antibiotic combination therapy in patients with chronic, treatment-resistant pouchitis. Aliment Pharmacol Ther 13(6):713–718

    Article  CAS  Google Scholar 

  25. Mimura T, Rizzello F, Helwig U et al (2002) Four-week open-label trial of metronidazole and ciprofloxacin for the treatment of recurrent or refractory pouchitis. Aliment Pharmacol Ther 16(5):909–917

    Article  CAS  Google Scholar 

  26. Herfarth HH, Long MD, Isaacs KL (2015) Use of biologics in pouchitis: a systematic review. J Clin Gastroenterol 49(8):647–654

    Article  CAS  Google Scholar 

  27. Mir F, Yousef MH, Partyka EK, Tahan V (2017) Successful treatment of chronic refractory pouchitis with vedolizumab. Int J Colorectal Dis 32(10):1517–1518

    Article  Google Scholar 

  28. Philpott J, Ashburn J, Shen B (2017) Efficacy of vedolizumab in patients with antibiotic and anti-tumor necrosis alpha refractory pouchitis. Inflamm Bowel Dis 23(1):E5–E6

    Article  Google Scholar 

  29. McLaughlin SD, Clark SK, Bell AJ et al (2009) Incidence and short-term implications of prepouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. Dis Colon Rectum 52(5):879–883

    Article  Google Scholar 

  30. Kuisma J, Jarvinen H, Kahri A, Färkkilä M (2004) Factors associated with disease activity of pouchitis after surgery for ulcerative colitis. Scand J Gastroenterol 39(6):544–548

    Article  CAS  Google Scholar 

  31. Wolf JM, Achkar JP, Lashner BA et al (2004) Afferent limb ulcers predict Crohn’s disease in patients with ileal pouch-anal anastomosis. Gastroenterology 126(7):1686–1691

    Article  Google Scholar 

  32. Pardi DS, Sandborn WJ (2006) Systematic review: the management of pouchitis. Aliment Pharmacol Ther 23(8):1087–1096

    Article  CAS  Google Scholar 

  33. Bell AJ, Price AB, Forbes A et al (2006) Pre-pouch ileitis: a disease of the ileum in ulcerative colitis after restorative proctocolectomy. Colorectal Dis 8(5):402–410

    Article  CAS  Google Scholar 

  34. Scott AD, Phillips RK (1989) Ileitis and pouchitis after colectomy for ulcerative colitis. Br J Surg 76(7): 668–669

    Article  CAS  Google Scholar 

  35. McLaughlin SD, Clark SK, Bell AJ et al (2009) An open study of antibiotics for the treatment of pre-pouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis. Aliment Pharmacol Ther 29(1):69–74

    Article  CAS  Google Scholar 

  36. Schmidt CM, Lazenby AJ, Hendrickson RJ, Sitzmann JV (1998) Preoperative terminal ileal and colonic resection histopathology predicts risk of pouchitis in patients after ileoanal pull-through procedure. Ann Surg 227(5): 654–662; discussion 663–665

    Article  CAS  Google Scholar 

  37. Iwata T, Yamamoto T, Umegae S, Matsumoto K (2007) Pouchitis and pre-pouch ileitis developed after restorative proctocolectomy for ulcerative colitis: a case report. World J Gastroenterol 13(4):643–646

    Article  Google Scholar 

  38. Slatter C, Girgis S, Huynh H, El-Matary W (2008) Pre-pouch ileitis after colectomy in paediatric ulcerative colitis. Acta Paediatr 97(3):381–383

    Article  Google Scholar 

  39. Thompson-Fawcett MW, Mortensen NJ, Warren BF (1999) “Cuffitis” and inflammatory changes in the columnar cuff, anal transitional zone, and ileal reservoir after stapled pouch-anal anastomosis. Dis Colon Rectum 42(3):348–355

    Article  CAS  Google Scholar 

  40. Wu B, Lian L, Li Y et al (2013) Clinical course of cuffitis in ulcerative colitis patients with restorative proctocolectomy and ileal pouch-anal anastomoses. Inflamm Bowel Dis 19(2):404–410

    Article  Google Scholar 

  41. O’Connell PR, Pemberton JH, Weiland LH et al (1987) Does rectal mucosa regenerate after ileoanal anastomosis? Dis Colon Rectum 30(1):1–5

    Article  Google Scholar 

  42. Shen B, Lashner BA, Bennett AE et al (2004) Treatment of rectal cuff inflammation (Cuffitis) in patients with ulcerative colitis following restorative proctocolectomy and ileal pouch-anal anastomosis. Am J Gastroenterol 99(8):1527–1531

    Article  Google Scholar 

  43. Wu B, Liu X, Shen B (2013) Refractory cuffitis resolved after temporary ileostomy and lysis of adhesion surgery. Inflamm Bowel Dis 19(3):E32–33

    Article  Google Scholar 

  44. Scarpa M, van Koperen PJ, Ubbink DT et al (2007) Systematic review of dysplasia after restorative proctocolectomy for ulcerative colitis. Br J Surg 94(5):534–545

    Article  CAS  Google Scholar 

  45. Wu XR, Kirat HT, Xhaja X et al (2014) The impact of mesenteric tension on pouch outcome and quality of life in patients undergoing restorative proctocolectomy. Colorectal Dis 16(12):986–994

    Article  Google Scholar 

  46. Gentilini L, Coscia M, Lombardi PM et al (2016) Ileal pouch-anal anastomosis 20 years later: is it still a good surgical option for patients with ulcerative colitis? Int J Colorectal Dis 31(12):1835–1843

    Article  Google Scholar 

  47. Lucha PA Jr, Fticsar JE, Francis MJ (2005) The strictured anastomosis: successful treatment by corticosteroid injections-report of three cases and review of the literature. Dis Colon Rectum 48(4): 862–865

    Article  Google Scholar 

  48. Panis Y, Poupard B, Nemeth J et al (1996) Ileal pouch/anal anastomosis for Crohn’s disease. Lancet 347(9005):854–857

    Article  CAS  Google Scholar 

  49. Keighley MR (2000) The final diagnosis in pouch patients for presumed ulcerative colitis may change to Crohn’s disease: patients should be warned of the consequences. Acta Chir Iugosl 47(4 Suppl 1):27–31

    CAS  PubMed  Google Scholar 

  50. Peyrègne V, Francois Y, Gilly F-N et al (2000) Outcome of ileal pouch after secondary diagnosis of Crohn’s disease. Int J Colorectal Dis 15(1)49–53

    Article  Google Scholar 

  51. Goldstein NS, Sanford WW, Bodzin JH (1997) Crohn’ s-like complications in patients with ulcerative colitis after total proctocolectomy and ileal pouch-anal anastomosis. Am J Surg Pathol 21(11):1343–1353

    Article  CAS  Google Scholar 

  52. Shen B, Fazio VW, Remzi FH et al (2007) Clinical features and quality of life in patients with different phenotypes of Crohn’s disease of the ileal pouch. Dis Colon Rectum 50(9):1450–1459

    Article  Google Scholar 

  53. Melton GB, Fazio VW, Kiran RP et al (2008) Long-term outcomes with ileal pouch-anal anastomosis and Crohn’s disease: pouch retention and implications of delayed diagnosis. Ann Surg 248(4):608–616

    PubMed  Google Scholar 

  54. Shen B, Achkar J-P, Lashner BA et al (2002) Irritable pouch syndrome: a new category of diagnosis for symptomatic patients with ileal pouch-anal anastomosis. Am J Gastroenterol 97(4):972–977

    Article  Google Scholar 

  55. Shen B, Fazio VW, Remzi FH et al (2005) Comprehensive evaluation of inflammatory and noninflammatory sequelae of ileal pouch-anal anastomoses. Am J Gastroenterol 100(1):93–101

    Article  Google Scholar 

  56. Shen B, Sanmiguel C, Parsi M et al (2004) Irritable pouch syndrome (IPS) is characterized by visceral hypersensitivity and poor quality-of-life (QOL) score. Gastroenterology 126(Suppl 2):A124

    Google Scholar 

  57. Shen B, Liu W, Remzi FH et al (2008) Enterochromaffin cell hyperplasia in irritable pouch syndrome. Am J Gastroenterol 103(9):2293–2300

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. General Surgery Unit, Department of Digestive Diseases, S. Orsola-Malpighi Hospital, Bologna, Italy

    Lorenzo Gentilini

Authors
  1. Gilberto Poggioli
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lorenzo Gentilini
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Maurizio Coscia
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Federica Ugolini
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Lorenzo Gentilini .

Editor information

Editors and Affiliations

  1. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

    Gilberto Poggioli

  2. General Surgery Unit, Department of Digestive Diseases, S. Orsola-Malpighi Hospital, Bologna, Italy

    Gilberto Poggioli

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer-Verlag Italia

About this chapter

Cite this chapter

Poggioli, G., Gentilini, L., Coscia, M., Ugolini, F. (2019). Long-term Complications after Surgical Treatment of Ulcerative Colitis. In: Poggioli, G. (eds) Ulcerative Colitis. Updates in Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-3977-3_12

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-3977-3_12

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-3976-6

  • Online ISBN: 978-88-470-3977-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation