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Vertebroplasty and Spinal Tumors

  • Chapter
Interventional Neuroradiology of the Spine

Abstract

The spine can be affected by several primary or secondary tumors, with progressive osteolysis of each part of the vertebra (i.e., posterior arch, pedicles, body), causing unsustainable local pain and motor impairment secondary to vertebral collapse [1]. In the last decade, prolongation of life expectancy in patients affected by neoplastic disease has been responsible for an increase in vertebral metastases, particularly in the case of cancer of the breast, lung, kidney and prostate cancer [2]. Approximately 70% of patients with secondary lesions have at least one vertebral lesion [3] (Table 11.1). Moreover, because of the improvement in survival related to implementation of cancer treatment, most methods (including vertebroplasty) have changed from being end-of-life palliative care to become part of management of chronic disease [4].

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References

  1. American Cancer Society: Cancer Facts and Figures 2007. Available at: http://www.cancer.org/acs/groups/content/@nho/documents/document/caff- 2007pwsecuredpdf.pdf. Accessed 3 September 2012

  2. Taneichi H, Kaneda K, Takeda N, Abumi K, Satoh S (1997) Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine. Spine (Phila Pa 1976) 22:239–245

    Article  CAS  Google Scholar 

  3. Byrne TN, Benzel EC, Waxman SG (2000) Epidural tumors. In: Byrne TN, Benzel EC, Waxman SG (eds) Diseases of the spine and spinal cord. Oxford University Press, New York, p 166–205

    Google Scholar 

  4. Rastogi R, Patel T, Swarm RA et al (2010) Vertebral augmentation for compression fractures caused by malignant disease. J Nat Comp Cancer Network 8: 1095–1102

    Google Scholar 

  5. Schiff D, O’Neill BP, Suman VJ (1997) Spinal epidural metastasis as the initial manifestation of malignancy: Clinical features and diagnostic approach. Neurology 49:452–456

    Article  PubMed  CAS  Google Scholar 

  6. Maranzano E, Latini P (1995) Effectiveness of radiation therapy without surgery in metastatic spinal cord compression: final results from a prospective trial. Int J Radiat Oncol Biol Phys 32:959–967

    Article  PubMed  CAS  Google Scholar 

  7. Rougraff BT, Kneisl JS, Simon MA (1993) Skeletal metastases of unknown origin: a prospective study of a diagnostic strategy. J Bone Joint Surg Am 75:1276–1281

    PubMed  CAS  Google Scholar 

  8. Lis E, Bilsky MH, Pisinski L et al (2004) Percutaneous CT-guided biopsy of osseous lesion of the spine in patients with known or suspected malignancy. Am J Neuroradiol 25:1583–1588

    PubMed  Google Scholar 

  9. Edelstyn GA, Gillespie PJ, Grebbell FS (1967) The radiological demonstration of osseous metastases: experimental observations. Clin Radiol 18:158–162

    Article  PubMed  CAS  Google Scholar 

  10. Buhmann Kirchhoff S, Becker C, Duerr HR, Reiser M, Baur-Melnyk A (2009) Detection of osseous metastases of the spine: comparison of high resolution multi-detector-CT with MRI. Eur J Radiol 69:567–573

    Article  Google Scholar 

  11. Taneichi H, Kaneda K, Takeda N, Abumi K, Satoh S (1997) Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine. Spine (Phila PA 1976) 22:239–245

    Article  CAS  Google Scholar 

  12. Katagiri H, Takahashi M, Inagaki J et al (1998) Clinical results of nonsurgical treatment for spinal metastases. Int J Radiat Oncol Biol Phys 42:1127–1132

    Article  PubMed  CAS  Google Scholar 

  13. Sørensen S, Helweg-Larsen S, Mouridsen H, Hansen HH (1994) Effect of high-dose dexamethasone in carcinomatous metastatic spinal cord compression treated with radiotherapy: a randomised trial. Eur J Cancer 30A:22–27

    Article  PubMed  Google Scholar 

  14. Patchell RA, Tibbs PA, Regine WF et al (2005) Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet 366:643–648

    Article  PubMed  Google Scholar 

  15. Saliou G, Kocheida M, Lehmann P et al (2010) Percutaneous vertebroplasty for pain management in malignant fractures of the spine with epidural involvement. Radiology 254:882–890

    Article  PubMed  Google Scholar 

  16. McDonald RJ, Trout AT, Gray LA et al (2008) Vertebroplasty in multiple myeloma: outcomes in a large patient series. Am J Neuroradiol 29:642–648

    Article  PubMed  CAS  Google Scholar 

  17. Fourney DR, Schomer DF, Nader R et al (2003) Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients. J Neurosurg 98(1Suppl.):21–30

    PubMed  Google Scholar 

  18. Cheung G, Chow E, Holden L et al (2006) Percutaneous vertebroplasty in patients with intractable pain from osteoporotic or metastatic fractures: a prospective study using quality-of-life assessment. Can Assoc Radiol J 57:13–21

    PubMed  Google Scholar 

  19. Pflugmacher R, Kandziora F, Schroeder RJ, Melcher I, Haas NP, Klostermann CK (2006) Percutaneous balloon kyphoplasty in the treatment of pathological vertebral body fracture and deformity in multiple myeloma: a one-year follow-up. Acta Radiol 47:369–376

    Article  PubMed  CAS  Google Scholar 

  20. Calmels V, Vallée JN, Rose M, Chiras J (2007) Osteoblastic and mixed spinal metastases: Evaluation of the analgesic efficacy of percutaneous vertebroplasty. Am J Neuroradiol 28:570–574

    PubMed  CAS  Google Scholar 

  21. Ahn H, Mousavi P, Roth S, Reidy D, Finkelstein J, Whyne C (2006) Stability of the metastatic spine pre-and post-vertebroplasty. J Spinal Disord Tech 19:178–182

    Article  PubMed  Google Scholar 

  22. Leigh WB, Draffin J, Taylor P, Theis JC, Walton M (2006). Experimental studies on thermal effects of cement during vertebroplasty. J Bone Joint Surg 88B(Suppl. 2):313

    Google Scholar 

  23. Bai B, Yin Z, Xu Q et al (2009) Histologic changes of an injectable rhBMP-2/calcium phosphate cement in vertebroplasty of rhesus monkey. Spine (Philla Pa 1976) 34:1887–1892

    Article  Google Scholar 

  24. Marcia S, Boi C, Dragani M et al (2012) Effectiveness of a bone substitute (CERAMENT™) as an alternative to PMMA in percutaneous vertebroplasty: 1-year follow-up on clinical outcome. Eur Spine J 21:S112–8

    Article  PubMed  Google Scholar 

  25. Fenton DS, Czervionke LF (2004) Image-guided spine interventions. Springer, New York p 69–93

    Google Scholar 

  26. Mathis JM. Vertebroplasty for vertebral fractures with intravertebral clefts (2002) Am J Neuroradiol 23:1619–1620

    PubMed  Google Scholar 

  27. Schaefer O, Lohrmann C, Markmiller M, et al (2003) Combined treatment of a spinal metastasis with radiofrequency heat ablation and vertebrioplasty. Am. J Roentgenol 180:1075–1077

    Article  Google Scholar 

  28. van der Linden E, Kroft LJ, Dijkstra PD, et al (2007) Treatment of vertebral tumor with posterior wall defect using image-guided radiofrequency ablation combined with vertebroplasty: preliminary results in patients. J Vasc Int Radiol 18: 741–747

    Article  Google Scholar 

  29. Gangi A, Buy X (2010) Percutaneous bone tumor management. Semin Intervent Radiol 27:124–136

    Article  PubMed  Google Scholar 

  30. Hirsch JA, Horsch AE, Jha R et al (2010) Practical management of malignant compression fractures. J NeuroIntervent Surg 2:219–220

    Article  Google Scholar 

  31. Luo J, Pollintine P, Dolan P, Adams MA (2011) Creep deformity of aging human vertebrae is accelerated following micro-damage. J Bone Joint Surg Br Proc 93B:487

    Google Scholar 

  32. Licht AW, Kramer W (2011) Radiofrequency kyphoplasty: a new method for the treatment of osteoporotic vertebral body compression fractures — a case report. J Miner Stoffwechs 18(Suppl.1):S26–S28

    Google Scholar 

  33. Pflugmacher R, Bornemann R, Randau T, Wirtz, DC (2011) Comparison of clinical and radiological data in treatment of patients with osteoporotic vertebral compression fractures with radiofrequency kyphoplasty or balloon kyphoplasty. GRIBOI 2011 — The 21st Interdisciplinary Research Conference On Injectable Osteoarticular Biomaterials and Bone Augmentation Procedures. Boston, 5-7 April

    Google Scholar 

  34. Luo J, Adams MA, Dolan P (2010) Vertebroplasty and kyphoplasty can restore normal spine mechanics following osteoporotic vertebral fracture. J Osteoporosis 1-9: article ID 729257

    Google Scholar 

  35. J. Gibson, et al., “Does cement distribution influence the mechanical outcome of vertebroplasty?” in Proceedings of the Society of Back Pain Research Meeting, Keele University, November 2008.

    Google Scholar 

  36. Baroud G, Crookshank M, Bohner M (2006) Highviscosity cement significantly enhances uniformity of cement filling in vertebroplasty: an experimental model and study on cement leakage. Spine 31:2562–2568

    Article  PubMed  Google Scholar 

  37. Loeffel M Ferguson SJ Nolte L.-P Nolte Kowal JH (2008) Vertebroplasty: experimental characterization of polymethyl-methacrylate bone cement spreading as a function of viscosity bone porosity and flow rate. Spine 33:1352–135

    Article  PubMed  Google Scholar 

  38. Sun K, Mendel E, Rhines L, et al (2006) Cement filling pattern has a significant effect on biomechanics of vertebroplasty. Proceedings of the 52nd Annual Meeting of the Orthopaedic Research Society, Chicago

    Google Scholar 

  39. Cortet B, Cotten A, Boutry N, et al (1997) Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myelomas. Rev Rhum Engl Ed 64:177–183

    PubMed  CAS  Google Scholar 

  40. Cotten A, Dewatre F, Cortet B, et al (1996) Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methylmethacrylate at clinical follow up. Radiology 200:525–530

    PubMed  CAS  Google Scholar 

  41. Appel NM, Gilula LA (2004) Percutaneous vertebroplasty in patients with spinal canal compromise. Am J Roentgenol 182}:947–951

    Article  Google Scholar 

  42. Saliou G, Kocheidael M, Lehmann P et al (2010) Percutaneous Vertebroplasty for pain management in malignant fracture of the spine with epidural involvement. Radiology 882–889

    Google Scholar 

  43. Uemura et al. (2005) Case report — Reduction of tumoral volume after sacroplasty with combined injection of PMMA & n-BCA n-butilcyanacrilate) in HCC metastasis. Bone cement used as an embolic agent for active bleeding in vertebroplasty of metastatic lesions. AJNR

    Google Scholar 

  44. Baba Y, Hayashi S, Ueno K, Nakajo M. Bone cement used as an embolic agent for active bleeding in vertebroplasty of metastatic lesions. Acta Radiol 48:1024–1027

    Google Scholar 

  45. Manfrè L (2006) Ischemic changes after vertebroplasty in epidural masses. Proc Am Soc Neuroradiol 1:385

    Google Scholar 

  46. Deramond H, Wright NT, Belkoff SM (1999) Temperature elevation caused by bone cement polymerization during vertebroplasty. Bone 25(2suppl):17S–21S

    Article  Google Scholar 

  47. Attivazione dose-dipendente di mRNA e proteine tumore-soppressore (TNF) dopo introduzione di PMMA. Kayamura. Spine 2006

    Google Scholar 

  48. Taneichi H, Kaneda K, Takeda N, Abumi K, Satoh S (1997) Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine. Spine (Phila Pa 1976) 22: 239–245

    Article  CAS  Google Scholar 

  49. Gailloud P (2002) Pain sedation with bupivacaine infiltration after vertebroplasty failure. J Vasc Interv Rad

    Google Scholar 

  50. Eyheremendy EP, De Luca SE, Sanabria E (2004) Percutaneous pediculoplasty in osteoporotic compression fractures. J Vasc Interv Radiol 15:869–74

    Article  PubMed  Google Scholar 

  51. Gangi A, Dietemann JL, Guth S et al (1998) Percutaneous laser photocoagulation of spinal osteoid osteomas under CT guidance. AJNR Am J Neuroradiol 19:1955–8

    PubMed  CAS  Google Scholar 

  52. Venbrux AV et al (2003) Image-guided percutaneous radiofrequency ablation for osteoid osteomas. J Vasc Interv Radiol 14: 375–380

    Article  PubMed  Google Scholar 

  53. Nour SG, Duerk JL, Lenin JS et al (2002) MR Imaging-guided radio-frequency thermal ablation of the lumbar vertebrae in porcine models. Radiology 224:452–462

    Article  PubMed  Google Scholar 

  54. Woertler K, Heindel W, Lindner N et al (2001) Osteoid osteoma: CT-guided percutaneous radiofrequency ablation and follow-up in 47 patients. J Vasc Interv Radiol 12:717–722

    Article  PubMed  CAS  Google Scholar 

  55. Pommershei W et al (2003) Sacroplasty: a treatment for sacral insufficiency fractures. Am J Neuroradiol 24:1003–1007

    Google Scholar 

  56. Garant M (2002) Sacroplasty: a new treatment for sacral insufficiency fracture. J Vasc Interv Radiol 13:1265–1267

    Article  PubMed  Google Scholar 

  57. Mehdizade A, Payer M, Martin JB et al (2004) Percutaneous vertebroplasty through a transdiscal access route after lumbar transpedicular instrumentation. Spine J 4:475–479

    Article  PubMed  Google Scholar 

  58. Gangi A et al (1994) Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. Am J Neuroradiol 15:83–86

    PubMed  CAS  Google Scholar 

  59. Perisinakis K, Papadokostakis G, Gourtsoyannis N et al (2004) Patient exposure and associated radiation risks from fluoroscopically guided vertebroplasty or kyphoplasty. Radiology 232:701–707

    Article  PubMed  Google Scholar 

  60. Seibert JA (2004) Vertebroplasty and kyphoplasty: do fluoroscopy operators know about radiation dose, and should they want to know? Radiology 232:633–634

    Article  PubMed  Google Scholar 

  61. Jaffe HL, Lichtenstein L (1942) Solitary unicameral bone cyst with emphasis on the roentgen picture, the pathologic appearance and the pathogenesis. Arch Surg 44:1004–1025

    Article  Google Scholar 

  62. Saccomanni B et al (2008) Aneurysmal bone cyst of spine: a review of literature. Arch Orthop Trauma Surg 128:1145–1147

    Article  PubMed  CAS  Google Scholar 

  63. Hay MC, Paterson D, Taylor TKF (1978) Aneurysmal bone cysts of the spine. J Bone Joint Surg Br 60B:406–411

    Google Scholar 

  64. Topouchian V, Mazda K, Pennecot GF et al (2004) Aneurysmal bone cysts in children: complications of fibrosing agent injection. Radiology 232:522–526

    Article  PubMed  Google Scholar 

  65. Boriani S, Bertoni F, Picci P et al (2001) Aneurysmal bone cyst of the mobile spine. Spine 26:27–35

    Article  PubMed  CAS  Google Scholar 

  66. Pennekamp W, Peters S, Schinkel C et al. Aneurysmal bone cyst of the cervical spine (2008) Eur Radiol 18: 2356–

    Article  PubMed  CAS  Google Scholar 

  67. Bollini G, Jouve JL, Cottalorda J, Petit P, Panuel M, Jacquemier M (1998) Aneurysmal bone cyst in children: analysis of twenty seven patients. J Pediatr Orthop B 7:274–285

    Article  PubMed  CAS  Google Scholar 

  68. Seller K, Jager M, Kramer R et al (2004) Occurrence of a segmental kyphosis after laminectomy of C2 for an aneurysmatic bone cysts: course and treatment strategy. Z Orthop Ihre Grenzgeb 142:83–87

    Article  PubMed  CAS  Google Scholar 

  69. Bush CH, Drane WE (2000) Treatment of an aneurysmal bone cyst of the spine by radionuclide ablation. Am J Neuroradiol 21:592–594

    PubMed  CAS  Google Scholar 

  70. Ramirez AR, Stanton RP (2002) Aneurysmal bone cyst in 29 children. J Pediatr Orthop 22:533–539

    PubMed  Google Scholar 

  71. Tokarz F, Jankowski R, Źukiel R (1993) Aneurysmal bone cyst of the skull and vertebral column treated operatively. Neurol Neurochir Pol 27: 533–540

    PubMed  CAS  Google Scholar 

  72. Daszkiewicz P, Roszkowski M, Grajkowska W (2004) Aneurysmal bone cyst of skull and vertebrae in children. Analysis of own material and review of the literature. Folia Neuropathol 42:25–30

    Google Scholar 

  73. Feigenberg SJ, Marcus RB, Zlotecki R et al (2001) Megavoltage radiotherapy for aneurysmal bone cysts. Int J Radiat Oncol Biol Phys 49:1243–1247

    Article  PubMed  CAS  Google Scholar 

  74. Dubois J, Chigot V, Grimard G, et al (2003) Sclerotherapy in aneurismal bone cysts in children: a review of 17 cases. Pediatr Radiol 33:365–372

    PubMed  Google Scholar 

  75. Dekeuwer P, Odent T, Cadilhac C et al (2003) Aneurysmal bone cyst of the spine in children: a 9-year follow-up of 7 cases and review of the literature. Rev Chir Orthop Reparatrice Appar Mot 89:97–106

    PubMed  CAS  Google Scholar 

  76. De Cristoforo R, Boriani S, Roversi R et al (1992) Selective arterial embolitation in the treatment of aneurismal bone cyst and angioma of bone. Skel Radiol 21:523–527

    Google Scholar 

  77. de Kleuver M, van der Heul RO, Veraart BE (1998) Aneurysmal bone cyst of the spine: 31 cases and the importance of the surgical approach. J Pediatr Orthop B 7:286–292

    Article  PubMed  CAS  Google Scholar 

  78. Rastogi S, Varshney MK, Trikha V, Khan SA, Choudhury B, Safaya R (2006) Treatment of aneurysmal bone cysts with percutaneous sclerotherapy using polidocanol. A review of 72 cases with longterm follow-up. J Bone Joint Surg Br 88:1212–1216

    CAS  Google Scholar 

  79. Shisha T, Nemeth T, Szoke G et al (2007) The dangers of intraosseous fibrosing agent injection in the treatment of bone cysts. The origin of major com plications shown in a rabbit model. Int Orthopaed 31:359–362

    CAS  Google Scholar 

  80. Falappa P, Fassari FM, Fanelli A et al (2002) Aneurysmal bone cysts: treatment with direct percutaneous ethibloc injection: long-term results. Cardiovasc Intervent Radiol 25:282–290

    Article  PubMed  Google Scholar 

  81. Adamsbaum C, Mascard E, Guinebretiere JM Kalifa G, Dubousset J (2003) Intralesional Ethibloc injections in primary aneurysmal bone cysts: an efficient and safe treatment. Skel Radiol 32:559–566

    Article  CAS  Google Scholar 

  82. Guarnieri G, Vassallo P, Muto M. (2010) Combined percutaneous and endovascular treatment of symptomatic aneurysmal bone cyst of the spine: clinical six months. Follow-up of six cases. Neuroradiol J 23:74–84

    Google Scholar 

  83. Motamedi D, Learch TJ, Ishimitsu DN et al (2009) Thermal ablation of osteoid osteoma: overview and step-by-step guide. Radiographics 29:2127–2141

    Article  PubMed  Google Scholar 

  84. Rosenthal DI, Hornicek FJ, Wolfe MW et al (1998) Percutaneous radiofrequency coagulation of osteoid osteoma compared with operative treatment. J Bone Joint Surg Am 80:815–821

    PubMed  CAS  Google Scholar 

  85. Rosenthal DI, Springfield DS, Gebhardt MC, Rosenberg AE, Mankin HJ (1995) Osteoid osteoma: percutaneous radio-frequency ablation. Radiology 197:451–454

    PubMed  CAS  Google Scholar 

  86. Rosenthal DI, Hornicek FJ, Torriani M, Gebhardt MC, Mankin HJ (2003) Osteoid osteoma: percutaneous treatment with radiofrequency energy. Radiology 229:171–175

    Article  PubMed  Google Scholar 

  87. Vanderschueren GM, Taminiau AHM, Obermann WR, Bloem JL (2002) Osteoid osteoma: clinical results with thermocoagulation. Radiology 224:82–86

    Article  PubMed  Google Scholar 

  88. Cioni R, Consoli V, Bartolozzi C (2004) CT-guided radiofrequency ablation of osteoid osteoma: longterm results. Eur Radiol 14:1203–1208

    Article  PubMed  Google Scholar 

  89. Lindner NJ, Ozaki T, Roedl R, Gosheger G, Winkelmann W, Wörtler K (2001) Percutaneous radiofrequency ablation in osteoid osteoma. J Bone Joint Surg Br 83:391–396

    Article  PubMed  CAS  Google Scholar 

  90. Laus M, Albisinni U, Alfonso C, Zappoli FA (2007) Osteoid osteoma of the cervical spine: surgical treatment or percutaneous radiofrequency coagulation? Eur Spine J 16:2078–2082

    Article  PubMed  CAS  Google Scholar 

  91. Dagi TF Schmidek HH (1990) Vascular tumors of the spine. In: Sundaresan N Schmidek HH Schiller AL (eds) Tumors of the spine: diagnosis and clinical management. Saunders Philadelphia p 181–19

    Google Scholar 

  92. Fox M, Onofrio B (1993) The natural history and management of symptomatic and asymptomatic vertebral hemangiomas. J Neurosurg 78:36–45

    Article  PubMed  CAS  Google Scholar 

  93. Pastushyn A, Slinko E, Mirzoyeva G et al (1998) Vertebral hemangiomas: diagnosis, management, natural history and clinicopathological correlates in patients. Surg Neurol 50:535–547

    Article  PubMed  CAS  Google Scholar 

  94. Healy M, Herz DA, Pearl L (1983) Spinal hemangiomas. Neurosurgery 13:689–691

    Article  PubMed  CAS  Google Scholar 

  95. Nguyen JP, Djindjian M, Gaston A (1987) Vertebral hemangiomas presenting with neurologic symptoms. Surg Neurol 27:391–397

    Article  PubMed  CAS  Google Scholar 

  96. Krueger EG (1961) Vertebral hemangioma with com-pression spinal cord. J Neurosurg 18:331–338

    Article  PubMed  CAS  Google Scholar 

  97. Acosta F, Chou D, Ames CP et al (2008) Comprehensive management of symptomatic and aggressive vertebral hemangiomas. Neurosurg Clin N Am 19:17–29

    Article  PubMed  Google Scholar 

  98. Castel E, Lazennec JY, Chiras J et al (1993) Acute spinal cord compression due to intraspinal bleeding from a vertebral hemangioma. J Vasc Interv Radiol 8:244–248

    Google Scholar 

  99. Kiroglu Y, Benek B, Yagci B, Cirak B, Tahta K (2009) Surgical spinal cord compression caused by vertebral hemangioma being symptomatic during pregnancy. Neurology 71:487–492

    Google Scholar 

  100. Guarnieri G, Muto M, Vassallo P et al (2009) Vertebroplasty as treatment of aggressive and symptomatic vertebral hemangiomas: up to 4 years of followup. Neuroradiology 51:471–476

    Article  PubMed  CAS  Google Scholar 

  101. Manfre L et al (2002) La vertebroplastica nelle neoplasie del rachide. Riv Neuroradiol 15:461–472

    Google Scholar 

  102. Deramond H (2003) Vertebroplasty for pain relief. Riv Neuroradiol 16:767–770

    Google Scholar 

  103. Brunot S, Berge J, Barreau X, Ménégon P, Dousset V (2005) Long term clinical follow up of vertebral hemangiomas treated by percutaneous vertebroplasty. J Radiol 86:41–47

    Article  PubMed  CAS  Google Scholar 

  104. Feydy, Cognard C, Chiras J (1996) Acrylic vertebroplasty in symptomatic cervical vertebral haemangiomas: report of 2 cases. Neuroradiology 38:389–391

    Article  PubMed  CAS  Google Scholar 

  105. Dousset V, Senegas U et al (1996) Asymptomatic cervical ha haemangioma treated by percutaneous vertebroplasty. Neuroradiology 38:392–394

    Article  PubMed  CAS  Google Scholar 

  106. Cheen L, Zhang C, Tang T (2007) Cement vertebroplasty combined with ethanol injection in the treatment of vertebral haemangioma. Chin Med J 120:1136–1139

    Google Scholar 

  107. Doppman J, Oldfield E, Heiss J et al (2000) Symptomatic vertebral hemangiomas: treatment by means of direct intralesional injection of Ethanol. Radiology 214:314–348

    Google Scholar 

  108. Gangi A, Kastler B, Dietmann JL et al (1994) Injection of alcohol into bone metastases under CT guidance. J Comput Assist Tomogr 18:932–935

    Article  PubMed  CAS  Google Scholar 

  109. Muto M, Muto E, Izzo R et al (2005) La vertebroplastica nel trattamento delle sindromi algiche del rachide. Radiol Med 109:208–219

    PubMed  Google Scholar 

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  1. Neuroradiology Department, A. Cardarelli Hospital, Naples, Italy

    Mario Muto

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  1. Luigi Manfrè
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  2. Gianluigi Guarnieri
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Manfrè, L., Guarnieri, G., Muto, M. (2013). Vertebroplasty and Spinal Tumors. In: Muto, M. (eds) Interventional Neuroradiology of the Spine. Springer, Milano. https://doi.org/10.1007/978-88-470-2790-9_11

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