Abstract
In obese patients a higher rate of cardiac output fraction is directed from the brain and other organs to adipose tissue. The anesthetic agents stored in fat depots will return to the circulation when the administration of anesthetic is discontinued and recovery from anesthesia can be delayed. A significative reduction of opioid consumption has been demonstrated with xenon anesthesia. Xenon may inhibit postoperative proinflammatory imbalance of cytokine production in morbidly obese patients undergoing elective surgery. The type of opioid used during general anesthesia in the morbidly obese can also influence recovery and the postoperative period. Dexmedetomidine significantly attenuates postoperative pain and reduces opioid and volatile anesthetic requirements in morbidly obese patients, without causing any cardio-respiratory depression and ensuring faster neuromuscular recovery and smooth emergence.
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Giunta, F., Salvo, C.D., Rubino, A., Marini, E. (2013). Does Choice of Inhaled Anesthetic Agent Matter?. In: Leykin, Y., Brodsky, J. (eds) Controversies in the Anesthetic Management of the Obese Surgical Patient. Springer, Milano. https://doi.org/10.1007/978-88-470-2634-6_18
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DOI: https://doi.org/10.1007/978-88-470-2634-6_18
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