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Demyelinating Diseases

  • Kelly K. Koeller
  • Frederik Barkhof
Conference paper

Abstract

The oligodendrocyte, predominantly found in the white matter, is the cell responsible for myelin production. As a general rule, demyelinating diseases result from either attacks on this cell or failure of these cells to regenerate under normal conditions. As a result, focal or diffuse myelin loss occurs. Multiple sclerosis (MS) is the prototypical white matter disease. Many other diseases may mimic its appearance on imaging studies. Although not an exhaustive list, this review highlights the important imaging manifestations that allow more specific diagnosis of these demyelinating diseases.

Keywords

Multiple Sclerosis White Matter Progressive Multifocal Leukoencephalopathy Demyelinating Disease Progressive Multifocal Leukoencephalopathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • Kelly K. Koeller
    • 1
  • Frederik Barkhof
    • 2
  1. 1.Mayo ClinicRochesterUSA
  2. 2.Department of RadiologyVU University Medical CenterAmsterdamThe Netherlands

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