Abstract
The oligodendrocyte, predominantly found in the white matter, is the cell responsible for myelin production. As a general rule, demyelinating diseases result from either attacks on this cell or failure of these cells to regenerate under normal conditions. As a result, focal or diffuse myelin loss occurs. Multiple sclerosis (MS) is the prototypical white matter disease. Many other diseases may mimic its appearance on imaging studies. Although not an exhaustive list, this review highlights the important imaging manifestations that allow more specific diagnosis of these demyelinating diseases.
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Koeller, K.K., Barkhof, F. (2012). Demyelinating Diseases. In: Hodler, J., von Schulthess, G.K., Zollikofer, C.L. (eds) Diseases of the Brain, Head & Neck, Spine 2012–2015. Springer, Milano. https://doi.org/10.1007/978-88-470-2628-5_9
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DOI: https://doi.org/10.1007/978-88-470-2628-5_9
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