Abstract
Sudden death, myocardial infarction and heart failure contribute significantly to cardiovascular mortality in the general population and are a common manifestation of coronary artery disease [1]. Acute coronary syndrome (ACS) and sudden death may represent the first manifestation of CAD in about 50% of patients. Furthermore, while the hospital mortality of patients with ACS has greatly improved in the past 20 years, out of hospital deaths are not declining. The main problem is therefore our poor ability to recognize those patients before the appearance of the manifestation of CAD. In fact, while it is relatively easy to identify and treat a patient with symptomatic CAD this is not true for the other individuals. It is therefore of paramount importance to identify those patients at risk of developing an acute manifestation of CAD prior to any clinical event. Although a significant coronary stenosis can often develop prior to ACS, it is clear now that about 50% of the acute events are caused by the complication of nonstenotic coronary segments [2, 3].
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Casolo, G. (2012). Screening and High CV Risk Patients. In: Cademartiri, F., Casolo, G., Midiri, M. (eds) Clinical Applications of Cardiac CT. Springer, Milano. https://doi.org/10.1007/978-88-470-2522-6_29
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DOI: https://doi.org/10.1007/978-88-470-2522-6_29
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