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Hemocoagulative Problems in the Critically Ill Patient pp 227–236Cite as

Coagulation Disorders After Central Nervous System Injury

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Abstract

Almost any injury to the brain may initiate disturbances in local and systemic coagulation. This statement is particularly true for subarachnoid hemorrhage, traumatic brain injuries, and cranial and spinal dural arteriovenous fistulae. The pathogenesis of coagulative disorders is highlighted from both a genetic and a structural biology perspective, along with a discussion of predictive biomarkers and clinical risk factors to guide the selection of eligible patients for primary prevention. This comprehensive review allows a better understanding of the coagulative disorders affecting patients harboring CNS diseases and accordingly offers new insights into their pharmacological and surgical treatment.

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Author information

Authors and Affiliations

  1. Anesthesia and Intensive Care, University of Trieste, Cattinara Hospital, Trieste, Italy

    Lara Prisco & Giorgio Berlot

  2. Department of Neurosurgery, University of Trieste, Cattinara Hospital, Strada di Fiume 447, 34149, Trieste, Italy

    Mario Ganau & Giorgio Berlot

Authors
  1. Lara Prisco
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  2. Mario Ganau
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  3. Giorgio Berlot
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Corresponding author

Correspondence to Lara Prisco .

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Editors and Affiliations

  1. , Department of Anesthesia and Intensive C, University of Trieste, Strada di Fiume 447, Trieste, I-34149, Italy

    Giorgio Berlot

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Prisco, L., Ganau, M., Berlot, G. (2012). Coagulation Disorders After Central Nervous System Injury. In: Berlot, G. (eds) Hemocoagulative Problems in the Critically Ill Patient. Springer, Milano. https://doi.org/10.1007/978-88-470-2448-9_15

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  • DOI: https://doi.org/10.1007/978-88-470-2448-9_15

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  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2447-2

  • Online ISBN: 978-88-470-2448-9

  • eBook Packages: MedicineMedicine (R0)

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