The HPA Axis and the Regulation of Energy Balance


The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine complex comprising the hypothalamus, hypophysis, and peripheral adrenal glands, all of which are joined in a feedback-loop-generating network of neural and chemical communications. The HPA is fundamental for the regulation of basic functions such as eating, drinking, reproduction, locomotion, and response to stress, thereby assuring individual and species survival.


Brown Adipose Tissue ACTH Secretion Zona Fasciculata Zona Reticularis Orexigenic Effect 
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© Springer-Verlag Italia 2012

Authors and Affiliations

  1. 1.Novartis Farma S.p.A.Saronno (Varese)Italy

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