The History of Research on Percutaneous, Transapical, and Sutureless Aortic Valve Replacement

  • Thierry Aymard
  • Thierry Carrel


A large number of scientific inventions evolved from research in different fields of interest. Only a few people with a visionary mind are able to see the future practical implications that transform a good idea into revolutionary process. For over 30 years the surgical replacement of a diseased aortic valve represented the golden standard of curative treatment for severe symptomatic aortic valve stenosis and significant regurgitation. Only recently has the operative risk declined crucially and the functional results are excellent. Long-term survival is very satisfactory, even for patients >80 years of age and has become close to that of non-operated patients of the same age. Despite these excellent results, surgery was found to be practiced preferentially in patients in good condition, whereas a substantial proportion of patients were not referred to surgery because the perioperative risk was estimated to be high owing to advanced age or significant comorbidities [1]. These patients would need an alternative technique to replace the diseased valve in order to re-establish normal valvular function. Recently, the development of two new techniques has changed the approach of patients considered to be at high risk of being refused conventional intervention: the insertion of a sutureless prosthesis and thus reducing substantially the surgery time and the transcatheter technique known as transcatheter aortic valve implantation (TAVI) allowing a tremendous decrease in the invasiveness of surgery. This new concept could profit from the already well-established method of cardiac catheterization.


Aortic Valve Transcatheter Aortic Valve Implantation Prosthetic Heart Valve Ball Valve Left Ventricular Apex 
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Copyright information

© Springer-Verlag Italia 2013

Authors and Affiliations

  1. 1.Clinic for Cardiovascular Surgery, Inselspital BerneBerne University Hospital and University of BerneBerneSwitzerland

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