Evolution of Homografts and Prosthetic Heart Valves

  • Marco Picichè


The history of heart valve replacement research comprises three rubrics: homografts, bioprostheses, and mechanical heart valves. The first prosthesis implanted was a mechanical valve in 1952. In rapid and overlapping succession, and despite numerous difficulties and failures, all three replacement types were in use by the early 1960s. Shape, design, size, volume, strength, durability, biocompatibility, ease of implantation, noise—every aspect was investigated in a swirl of industry competition to describe the optimal valve profile. Initially, mechanical valves attracted the most attention—witness the hundreds of models created at that time vs today where stented, stentless, transcatheter, and sutureless biological prostheses claim the spotlight.


Aortic Valve Heart Valve Mechanical Valve Prosthetic Heart Valve Mechanical Heart Valve 
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Copyright information

© Springer-Verlag Italia 2013

Authors and Affiliations

  1. 1.Cardiac Surgery UnitSan Filippo Neri HospitalRomeItaly

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