From Research on Hibernation and Hypothermia to Recent Advances in Cardiopulmonary Bypass

  • Isabelle Plamondon
  • Edoardo Gasparotto


For many years, progress in cardiac surgery were limited by the inability to operate within the empty heart under direct vision. There have been several methods devised in the effort to obtain intracardiac exposure with a dry field. The early models of heart-lung machines developed were not widely applicable with safety to the human patient. The other avenue of approach has been the attempt to reduce the metabolic demand until circulation can be interrupted for periods of time long enough without recourse to extracorporeal pumps. General hypothermia has been investigated as a means of reducing the oxygen requirements of the body to allow deliberate and extensive intracardiac maneuvers.


Ventricular Fibrillation Circulatory Arrest Deep Hypothermic Circulatory Arrest Biocompatible Surface Lung Machine 
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Copyright information

© Springer-Verlag Italia 2013

Authors and Affiliations

  1. 1.Critical Care Division, Institut Universitaire de Cardiologie et de Pneumologie de QuébecQuébecCanada
  2. 2.Cardiac Surgery Unit, Department of Cardiovascular ScienceSan Bortolo HospitalVicenzaItaly

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