Post Radiation-therapy Morphologic MR Imaging
Radiation therapy (RT) is responsible for cellular damage that affects not only cancer cells but also healthy brain and endothelial cells causing toxic effects on enzyme systems. These effects continue in the targeted organ for many months to reach the optimal performance after at least 3–6 months and in some cases, years after the end of treatment, although effects on healthy cells persist over time. In many cases post-RT alterations are associated with concomitant chemotherapy changes which strengthen the harmful effect.
KeywordsWhite Matter Intracranial Hypertension Optic Neuritis Radiation Necrosis Periventricular White Matter
- 1.Edelman RR, Hesselink JR, Zlatkin MB et al (2006) Clinical magnetic resonance imaging. Saunders, PhiladelphiaGoogle Scholar