• M. Cristina Digilio
  • Bruno Dallapiccola
  • Bruno Marino


Genetics plays an important role in the etiology of congenital heart defects (CHDs), as demonstrated by clinical, epidemiological, embryological, and molecular studies. In fact, the finding of inherited CHDs, the association of CHDs with extracardiac defects and genetic syndromes and increasing knowledge about disease-associated genes are shedding light onto the role of genetic factors in determing CHDs.


Down Syndrome Ventricular Septal Defect Deletion Syndrome Double Outlet Right Ventricle Alagille Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia 2012

Authors and Affiliations

  • M. Cristina Digilio
  • Bruno Dallapiccola
  • Bruno Marino
    • 1
  1. 1.Pediatric Cardiology, Department of PediatricsSapienza UniversityRomeItaly

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