Pharmacological Basics of Clinical Anaesthesia: Analgesia
Opioid agents are essential for achieving the suppression of reflex responses to noxious surgical and anaesthetic stimulations, one of the major objectives of anaesthesia. They interfere with the transmission of nociceptive impulses at the spinal cord and the brain, thereby reducing the resulting reflex responses to pain.
KeywordsDrug Effect Cerebral Perfusion Pressure Pharmacological Basic Noxious Stimulation Clinical Anaesthesia
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- 1.Ausems ME, Vuyk J, Hug CC et al (1988) Comparison of a computer assisted infusion versus intermittent bolus administration of alfentanil as a supplement to nitrous oxide for lower abdominal surgery. Anesthesiology 88:851–861Google Scholar