Methodology of Noninvasive Positive Pressure Ventilation in Acute Respiratory Failure

  • G. U. Meduri
Conference paper


In many patients with acute respiratory failure (ARF), noninvasive positive pressure ventilation (NPPV) via a mask can be equally as effective in improving the pathophysiology of respiratory failure and correcting gas exchange abnormalities as conventional ventilation via an endotracheal tube [1]. When effective, NPPV avoids the complications associated with endotracheal intubation, improves patient comfort and preserves airway defense mechanisms, speech and swallowing. Furthermore, NPPV provides greater flexibility in instituting and removing mechanical ventilation (MV).


Chronic Obstructive Pulmonary Disease Continuous Positive Airway Pressure Endotracheal Intubation Acute Respiratory Failure Pressure Support Ventilation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Meduri GU (1996) Noninvasive positive-pressure ventilation in patients with acute respiratory failure. Chest Clin N Am 17:513–553CrossRefGoogle Scholar
  2. 2.
    Meduri GU, Turner RE, Abou-Shala N et al (1996) Noninvasive positive pressure ventilation via face mask: first-line intervention in patients with acute hypercapnic and hypoxemic respiratory failure. Chest 109:179–193PubMedCrossRefGoogle Scholar
  3. 3.
    Brochard L, Mancebo J, Wysocki M et al (1995) Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 333:817–822PubMedCrossRefGoogle Scholar
  4. 4.
    Carrey Z, Gottfried SB, Levy RD (1990) Ventilatory muscle support in respiratory failure with nasal positive pressure ventilation. Chest 97:150–158PubMedCrossRefGoogle Scholar
  5. 5.
    Appendini L, Patessio A, Zanaboni S et al (1994) Physiologic effects of positive end-expiratory pressure and mask pressure support during exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 149:1069–1076PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 1997

Authors and Affiliations

  • G. U. Meduri

There are no affiliations available

Personalised recommendations