Understanding the Incidence and Long-term Outcome of ARDS
Despite the advances made in our understanding of the pathophysiology of ARDS and despite the considerable attention focused on potential new therapies aimed at mitigating the effects of ARDS, we continue to have surprisingly little information regarding the incidence and outcome of ARDS. Previous estimates of the incidence of ARDS in the US vary from 1.5 to 71 cases per 100,000 while mortality ranges vary by almost 10-fold. One explanation for this variation is that ARDS is being measured inconsistently across different studies, for example, by using inconsistent definitions or failing to capture the full duration of the illness process, and thereby underestimating mortality. Alternatively, true variation could exist in both the incidence and mortality between different regions and populations as reflections of differences in underlying risk factors and in patient management.
KeywordsSystemic Inflammatory Response Syndrome Critical Illness Multisystem Organ Failure Organ Failure Score Resp Crit
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