Which Patients with Dilated Cardiomyopathy May Really Benefit from Dual-chamber Pacing?
The reduction of mitral regurgitation. Sequential pacing with short AV interval leads to an activated atrium during the expulsive stage of the left ventricle, thus determining the reduction of the ventriculoatrial gradient, the diastolic mitral regurgitation and the early mitral valve closure [1, 7].
A better utilization of the Frank-Starling mechanism obtained by restoring the atrioventricular synchronization .
A better sequence of the activation-relaxation induced by sequential pacing compared with that realized by the normal conduction pathways [3, 4, 9]. This mechanism may reduce the apical activation delay, that it’s very pronounced in dilated hearts, and, consequently, the wall stress.
KeywordsMitral Regurgitation Dilate Cardiomyopathy Sequential Pace Hemodynamic Mechanism Group Congestive Heart Failure
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