Inappropriate Sinus Tachycardia: Mechanism and Therapy
Inappropriate sinus tachycardia (IST) is a chronic non-paroxysmal tachycardia arising from the sinus node, and is characterized by a sinus rate that is excessive with respect to the level of physical or psychological stress. Apart from early contributions given by Codvelle and Boucher  in 1939 and by Wising  in 1941, the first clinical report dedicated to this particular arrhythmia was published in 1979 by Bauernfeind et al. . Although the concept of IST is obvious, there is no agreement on the quantitative criteria required for the diagnosis. This has resulted in substantial differences between published series of patients: for example all Bauernfeind’s patients had resting sinus rate > 100 , whereas 5 out of 6 patients reported by Morillo et al.  had normal resting heart rate even though reflecting an exaggerated rate response to physical activity.
KeywordsHeart Rate Variability Catheter Ablation Sinus Node Sinus Tachycardia Atrial Tachycardia
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