Inappropriate Sinus Tachycardia: Mechanism and Therapy

  • C. Pappone
  • G. Oreto
  • M. Rillo
  • S. Chierchia


Inappropriate sinus tachycardia (IST) is a chronic non-paroxysmal tachycardia arising from the sinus node, and is characterized by a sinus rate that is excessive with respect to the level of physical or psychological stress. Apart from early contributions given by Codvelle and Boucher [1] in 1939 and by Wising [2] in 1941, the first clinical report dedicated to this particular arrhythmia was published in 1979 by Bauernfeind et al. [3]. Although the concept of IST is obvious, there is no agreement on the quantitative criteria required for the diagnosis. This has resulted in substantial differences between published series of patients: for example all Bauernfeind’s patients had resting sinus rate > 100 [3], whereas 5 out of 6 patients reported by Morillo et al. [4] had normal resting heart rate even though reflecting an exaggerated rate response to physical activity.


Heart Rate Variability Catheter Ablation Sinus Node Sinus Tachycardia Atrial Tachycardia 
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Copyright information

© Springer-Verlag Italia 1998

Authors and Affiliations

  • C. Pappone
    • 1
  • G. Oreto
    • 2
  • M. Rillo
    • 1
  • S. Chierchia
    • 1
  1. 1.Reparto di CardiologiaOspedale S. RaffaeleMilanoItaly
  2. 2.Reparto di Medicina e CardiologiaUniversità di MessinaMessinaItaly

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