What Are the Electrophysiological Mechanisms of Perpetuation of Atrial Fibrillation?

  • M. A. Allessie
  • F. J. Chorro
  • M. C. E. F. Wijffels
  • F. Mast
  • R. Dorland


Atrial fibrillation (AF) is the most common arrhythmia in man, its incidence greatly increases with age resulting in a prevalence of more than 2% in the population over 60 years of age [1–3]. It therefore represents an important medical problem with a considerable impact on morbidity and quality of life, especially in the elderly. Because of thrombus formation in the left atrium and the associated risk of cerebrovascular accidents, although it is not immediately life threatening, on the long term the arrhythmia also carries a considerable mortality.


Atrial Fibrillation Conduction Velocity Spiral Wave Electrophysiological Mechanism Multiple Wavelet 
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Copyright information

© Springer-Verlag Italia 1998

Authors and Affiliations

  • M. A. Allessie
    • 1
  • F. J. Chorro
    • 1
  • M. C. E. F. Wijffels
    • 1
  • F. Mast
    • 1
  • R. Dorland
    • 1
  1. 1.Department of Physiology, Cardiovascular Research Institute MaastrichtMaastricht UniversityThe Netherlands

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