Abstract
In 1982, Pepe and Marini [1] pointed out the clinical importance of dynamic increase in end-expiratory lung volume and positive end-expiratory alveolar pressure in mechanically ventilated patients with airflow obstruction. This end-expiratory pressure was termed “occult, auto or intrinsic PEEP” (PEEPi) and is due to the positive end-expiratory elastic recoil pressure of the total respiratory system consequent to incomplete lung emptying. In patients with severe airflow obstruction, because the rate of the lung emptying is slow relative to the available expiratory duration, the expiration is interrupted by the subsequent breath before the relaxation volume of the respiratory system (Vr) is reached. The increase in end expiratory lung volume above Vr is termed dynamic pulmonary hyperinflation. Dynamic hyperinflation and PEEPi were detected not only in ventilated patients with airway obstruction but also in ventilated patients with other disorders [2–4] and in all ventilatory conditions in which a short expiratory time is used, as inverse ratio ventilation (5, 6].
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Antonaglia, V., Peratoner, A., De Simoni, L. (2000). Static and Dynamic Intrinsic PEEP and Respiratory Mechanics in Mechanically Ventilated COPD Patients. In: Gullo, A. (eds) Anesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.. Springer, Milano. https://doi.org/10.1007/978-88-470-2286-7_18
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DOI: https://doi.org/10.1007/978-88-470-2286-7_18
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