Pathophysiology of Liver Dysfunction in Sepsis

  • N. Brienza
Conference paper


Liver dysfunction is commonly associated with critical illness. Up to 54% of patients admitted to intensive care units present abnormal liver function tests. Severe liver dysfunction is reported to occur in 12–95% of adult respiratory distress syndrome patients and liver blood tests on the first day of diagnosis are predictive of survival [1]. Liver failure is a critical determinant of mortality in trauma [2], in intra-abdominal sepsis [2], and after cardiopulmonary bypass surgery [3].


Liver Dysfunction Adult Respiratory Distress Syndrome Intrahepatic Cholestasis Closing Pressure Cardiopulmonary Bypass Surgery 
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© Springer-Verlag Italia 2000

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  • N. Brienza

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