Update on respiratory distress syndrome
Respiratory distress syndrome (RDS), also known as hyaline membrane disease (HMD), is the most common cause of mortality and morbidity in premature infants. Approximately 1% of all newborns world/wide develop RDS. In the USA about 5 000 neonatal deaths/year are due to RDS . Over the last two decades mortality from RDS has dramatically decreased even for extremely premature newborns . Several factors are attributable to improved outcome, and namely: 1) better understanding of lung maturation; 2) improved perinatal management; 3) postnatal use of surfactant as replacement therapy; 4) improved ventilatory management; 5) overall improvement in managing extremely low birth weight infants. This review will highlight the advances in these areas.
KeywordsRespiratory Distress Syndrome Patent Ductus Arteriosus Lamellar Body Bronchopulmonary Dysplasia Conventional Mechanical Ventilation
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