Skip to main content
SpringerLink
Log in

Fetal anaesthesia for surgery

  • Chapter
Anaesthesia and Intensive Care in Neonates and Children

Part of the book series: Topics in Anaesthesia and Critical Care ((TIACC))

  • 104 Accesses

Abstract

After extensive experimental study, fetal surgery has been undertaken in humans in a very few centers in the world [1, 2]. The purpose of this surgery is to correct a malformation before its effects have definitively compromised neonatal and fetal prognosis. Examples of this concept are the surgical correction of congenital diaphragmatic hernia [3–5] or bilateral hydronephrosis [6]; both of these conditions have been successfully treated before birth in some human fetuses.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bargy F, Rouquet Y, Estève C, Toubas F, Gaudiche O, Meynaud L, Germain G (1987) Chirurgie in utero de la hernie diaphragmatique chez le singe Macaque. Chir Pediatr 28:108–111

    PubMed  CAS  Google Scholar 

  2. Harrison MR, Anderson J, Rosen MA, Ross NA, Hendrickx AG (1982) Anaesthetic, surgical and tocolytic management to maximize fetal-neonatal survival. J Pediatr Surg 17:115–121

    Article  PubMed  CAS  Google Scholar 

  3. Estève C, Toubas F, Gaudiche O, Leveque C, Bargy F, Rouquet Y, Sapin E, Murat I, Saint Maurice C (1992) Bilan de cinq années de chirurgie expérimentale in utero pour la réparation des hernies diaphragmatiques. Ann Fr Anaesth Reanim 11:193–200

    Article  Google Scholar 

  4. Harrison MR, Adzick NS, Longaker MT, Goldberg JD, Rosen MA, Filly RA, Evans MI, Golbus MS (1990) Successful repair in utero of a fetal diaphragmatic hernia after removal of herniated viscera from the left thorax. N Engl J Med 322:1582–1584

    Article  PubMed  CAS  Google Scholar 

  5. Harrison MR, Langer JC, Adzick NS, Golbus MS, Filly RA, Anderson RL, Rosen MA, Callen PW, Goldstein RB, de Lorimier AA (1990) Correction of congenital diaphragmatic hernia in utero V. Initial clinical experience. J Pediatr Surg 25:47–57

    Article  PubMed  CAS  Google Scholar 

  6. Crombleholme TM, Harrison MR, Langer JC, Longaker MT, Anderson RL, Slotnik NS (1988) Early experience with open fetal surgery for congenital hydronephrosis. J Pediatr Surg 23:1114–1121

    Article  PubMed  CAS  Google Scholar 

  7. Johnson MD, Birnbach DJ, Burchman C, Greene MF, Datta S, Ostheimer GW (1989) Fetal surgery and general anaesthesia: a case report and review. J Clin Anaesth 1:363–367

    Article  CAS  Google Scholar 

  8. Rosen MA (1992) Anaesthesia for fetal procedures and surgery. In: Shnider SM, Levinson G (eds) Anaesthesia for obstetrics. Williams and Wilkins, Baltimore, pp 281–295

    Google Scholar 

  9. Munson ES, Embro WJ (1977) Enflurane, isoflurane and halothane and isolated human uterine muscle. Anaesthesiology 46:11–14

    Article  CAS  Google Scholar 

  10. Naftalin NJ, McKay DM, Phear WPC, Goldberg AH (1977) The effects of halothane on pregnant and nonpregnant human myometrium. Anaesthesiology 46:15–19

    Article  CAS  Google Scholar 

  11. Palahniuk RJ, Shnider SM, Eger EI II (1974) Pregnancy decreases the requirement of inhaled anaesthetic agents. Anaesthesiology 41:82–83

    Article  CAS  Google Scholar 

  12. Palahniuk RJ, Cumming M (1977) Foetal deterioration following thiopentone-nitrous oxide anaesthesia in the pregnant ewe. Can Anaesth Soc J 24:361–370

    Article  PubMed  CAS  Google Scholar 

  13. Biehl DR, Cote J, Wade JG, Gregory GA, Sitar D (1983) Uptake of halothane by the foetal lamb in utero. Can Anaesth Soc J 30:24–27

    Article  PubMed  CAS  Google Scholar 

  14. Gregory GA, Wade JG, Biehl DR, Ong BY, Sitar DS (1983) Fetal anaesthetic requirement (MAC) for halothane. Anaesth Analg 62:9–14

    Article  CAS  Google Scholar 

  15. Lévêque C, Toubas F, Lepaul M, Poissonnier MH, Brossard Y, Saint-Maurice C (1989) Curarisation foetale au cours des exsanguinotransfusions réalisées in utero pour le traitement transfusionnel des iso-immunisations rhésus graves. Cah Anaesthesiol 37:479–482

    Google Scholar 

  16. Anand KJS, Hickey PR (1987) Pain and its effects in the human neonate and fetus. N Engl J Med 317:1321–1329

    Article  PubMed  CAS  Google Scholar 

  17. Anand KJS, Sippel WG, Ainsley-Green A (1987) Randomized trial of fentanyl anaesthesia in preterm neonates undergoing surgery: effects on stress response. Lancet 1:243–248

    Article  PubMed  CAS  Google Scholar 

  18. Eng M, Bonica JJ, Akamatsu TJ, Berges PU, Der Yuen D, Ueland K (1975) Maternal and fetal responses to halothane in pregnant monkeys. Acta Anaesth Scand 19:154–158

    Article  PubMed  CAS  Google Scholar 

  19. Palahniuk RJ, Shnider SM (1974) Maternal & fetal cardiovascular and acid-base changes during halothane and isoflurane anaesthesia in the pregnant ewe. Anaesthesiology 41:462–472

    Article  CAS  Google Scholar 

  20. Biehl DR, Tweed WA, Cote J, Wade JG, Sitar D (1983) Effect of halothane on cardiac output and regional flow in the fetal lamb in utero. Anaesth Analg 62:489–492

    Article  CAS  Google Scholar 

  21. Palahniuk RJ, Doig GA, Johnson GN, Pash MP (1980) Maternal halothane anaesthesia reduces cerebral blood flow in the acidotic sheep fetus. Anaesth Analg 59:35–39

    Article  CAS  Google Scholar 

  22. Yarnell R, Biehl DR, Tweed WA, Gregory GA, Sitar D (1983) The effect of halothane anaesthesia on the asphyxiated foetal lamb in utero. Can Anaesth Soc J 30:474–479

    Article  PubMed  CAS  Google Scholar 

  23. Shnider SM, Wright RG, Levinson G, Roizen MF, Wallis KL, Rolbin SH, Craft JB (1979) Uterine blood flow and plasma norepinephrine changes during maternal stress in the pregnant ewe. Anaesthesiology 50:524–527

    Article  CAS  Google Scholar 

  24. Eronen M, Pesonen E, Kurki T, Ylikorkala O, Hallman M (1991) The effects of indomethacin and a beta-sympathomimetic agent on the fetal ductus arteriosus during treatment of premature labor: a randomized double-blind study. Am J Obstet Gynecol 164:141–146

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. J. Hamza
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Simon
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Sacquin
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Anaesthesia and Intensive Care, Buzzi Children Hospital, Milan, Italy

    I. Salvo MD

  2. Department of Pediatrics, College of Medicine at Chicago, University of Illinois, Chicago, USA

    D. Vidyasagar MD

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Italia

About this chapter

Cite this chapter

Hamza, J., Simon, L., Sacquin, P. (1999). Fetal anaesthesia for surgery. In: Salvo, I., Vidyasagar, D. (eds) Anaesthesia and Intensive Care in Neonates and Children. Topics in Anaesthesia and Critical Care. Springer, Milano. https://doi.org/10.1007/978-88-470-2282-9_12

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-2282-9_12

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0043-8

  • Online ISBN: 978-88-470-2282-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation