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Chlamydia pneumoniae: Epidemiology

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Chlamydia pneumoniae
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Abstract

In 1989, the Chlamydia strain previously labelled TWAR was recognized as a third species of the Chlamydia genus on the basis of ultrastructural and DNA homology analysis and named Chlamydia pneumoniae [1].

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References

  1. Grayston JT, Kuo C-C, Campbell LA et al (1989) Chlamydia pneumoniae sp. nov. for Chlamydia sp. strain TWAR. Int J Syst Bacteriol 39: 88–90

    Article  Google Scholar 

  2. Leinonen M (1993) Pathogenetic mechanisms and epidemiology of Chlamydia pneumoniae. Eur Heart J 14: 57–61

    Article  PubMed  Google Scholar 

  3. Thom DH, Grayston JT (1991) Infections with Chlamydia pneumoniae strain TWAR. Clin Chest Med 12: 245–256

    PubMed  CAS  Google Scholar 

  4. Marrie TJ (1993) Chlamydia pneumoniae. Thorax 48: 1–4

    Article  PubMed  CAS  Google Scholar 

  5. Grayston JT, Campbell LA, Kuo C-C et al (1990) A new respiratory tract pathogen Chlamydia pneumoniae strain TWAR. J Infect Dis 161: 618–625

    Article  PubMed  CAS  Google Scholar 

  6. Beaty CD, Grayston JT, Wang S-P et al (1991) Chlamydia pneumoniae, strain TWAR, infection in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 144: 1408–1410

    PubMed  CAS  Google Scholar 

  7. Blasi F, Legnani D, Lombardo VM et al (1993) Chlamydia pneumoniae infection in acute exacerbations of COPD. Eur Respir J 6: 19–22

    PubMed  CAS  Google Scholar 

  8. Saikku P (1992) The epidemiology and significance of Chlamydia pneumoniae. J Infect 25: 27–34

    Article  PubMed  Google Scholar 

  9. Kleemola M, Saikku P, Visakorpi R et al (1988) Epidemics of pneumonia caused by TWAR, a new chlamydial organism, in military trainees in Finland. J Infect Dis 157: 230–236

    Article  PubMed  CAS  Google Scholar 

  10. Marrie TJ, Grayston JT, Wang S-P et al (1987) Pneumonia associated with TWAR strain of Chlamydia. Ann Intern Med 106: 507–511

    PubMed  CAS  Google Scholar 

  11. Hahn DL, Dodge RW, Golubjatnikov R (1991) Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma. JAMA 266: 225–230

    Article  PubMed  CAS  Google Scholar 

  12. Allegra L, Blasi F, Centanni S et al (1994) Acute exacerbations of asthma in adults: role of Chlamydia pneumoniae infection. Eur Respir J 7: 2165–2168

    Article  PubMed  CAS  Google Scholar 

  13. Pether JVS, Wang S-P, Grayston JT (1989) Chlamydia pneumoniae strain TWAR as the cause of an outbreak in a boys’ school previously called Psittacosis. Epidemiol Infect 103: 395–400

    Article  PubMed  CAS  Google Scholar 

  14. Yamazaki T, Nakada H, Sakurai N et al (1990) Transmission of Chlamydia pneumoniaein young children in a Japanese family. J Infect Dis 162: 1390–1392

    Article  PubMed  CAS  Google Scholar 

  15. Mordhorst CH, Wang S-P, Grayston JT (1992) Outbreak of Chlamydia pneumoniaeinfection in four farm families. Eur J Clin Microbiol Infect Dis 11: 617–620

    Article  PubMed  CAS  Google Scholar 

  16. Aldous MB, Grayston JT, Wang S-P (1992) Seroepidemiology of Chlamydia pneumoniaeTWAR infection in Seattle families, 1966–1979. J Infect Dis 166: 646–649

    Article  PubMed  CAS  Google Scholar 

  17. Blasi F, Cosentini R, Denti F et al (1994) Two family outbreaks of Chlamydia pneumoniaeinfection. Eur Respir J 7: 102–104

    Article  PubMed  CAS  Google Scholar 

  18. Blasi F, Cosentini R, Clerici Schoeller M et al (1993) Chlamydia pneumoniae seroprevalence in immunocompetent and immunocompromised populations in Milan. Thorax 48: 1261–1263

    Article  PubMed  CAS  Google Scholar 

  19. Augenbraun MH, Roblin MR, Chirwing K et al (1991) Isolation of Chlamydia pneumoniaefrom lungs of patients infected with the human immunodeficiency virus. J Clin Microbiol 29: 401–402

    PubMed  CAS  Google Scholar 

  20. Clark R, Mushatt D, Fazal B (1991) Case report: Chlamydia pneumoniae pneumonia in HIV-infected man. Eur J Med Sci 302: 155–156

    CAS  Google Scholar 

  21. Gaydos CA, Flower CL, Gill BJ et al (1993) Detection of Chlamydia pneumoniae by polymerase chain reaction-enzyme immunoassay in an immunocompromised population. Clin Infect Dis 17: 718–723

    Article  PubMed  CAS  Google Scholar 

  22. Blasi F, Boschini A, Cosentini R et al (1994) Outbreak of Chlamydia pneumoniae infection in an ex injection-drug users community. Chest 105: 812–815

    Article  PubMed  CAS  Google Scholar 

  23. Grönhagen-Riska C, Saikku P, Riska H et al (1992) Antibodies to a TWAR — a novel type of Chlamydia — in sarcoidosis. In: Grassi C, Rizzato G, Pozzi E (eds) Sarcoidosis and other granulomatous disorders. Elsevier, Amsterdam, pp 297–301

    Google Scholar 

  24. Poulakkainen M, Campbell LA, Kuo C-C et al (1996) Serological response to Chlamydia pneumoniae in patients with sarcoidosis. J Infect 33: 199–205

    Article  Google Scholar 

  25. Dahlen GH, Boman J, Birgander LS, Lindblom B (1995) Lp(a) lipoprotein, IgG, IgA, and IgM antibodies to Chlamydia pneumoniae and HLA class II genotype in early coronary artery disease. Atherosclerosis 114: 165–174

    Article  PubMed  CAS  Google Scholar 

  26. Saikku P, Leinonen M, Mattila K et al (1988) Serological evidence of an association of a novel chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 29: 983–986

    Article  Google Scholar 

  27. Thom DH, Wang S-P, Grayston JT et al (1991) Chlamydia pneumoniae strain TWAR antibody and angiographically demonstrated coronary artery disease. Arterioscler Thromb 11: 547–551

    Article  PubMed  CAS  Google Scholar 

  28. Saikku P, Leinonen M, Tenkanen L et al (1992) Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study. Ann Intern Med 116: 273–278

    PubMed  CAS  Google Scholar 

  29. Linnanmaki E, Leinonen M, Mattila K (1993) Chlamydia pneumoniae-specific circulating immune complexes in patients with chronic coronary heart disease. Circulation 87: 1130–1134

    PubMed  CAS  Google Scholar 

  30. Shor A, Kuo C-C, Patton DL (1992) Detection of Chlamydia pneumoniae in coronary arterial fatty streaks and atheromatous plaques. S Afr Med J 82: 158–161

    PubMed  CAS  Google Scholar 

  31. Kuo C-C, Shor A, Campbell LA et al (1993) Demonstration of Chlamydia pneumoniaein atherosclerotic lesions of coronary arteries. J Infect Dis 167: 841–849

    Article  PubMed  CAS  Google Scholar 

  32. Campbell LA, O’Brien ER, Cappuccio AL et al (1995) Detection of Chlamydia pneumoniaeTWAR in human coronary atherectomy tissues. J Infect Dis 172: 585–588

    Article  PubMed  CAS  Google Scholar 

  33. Kuo C-C, Grayston JT, Campbell LA et al (1995) Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15–34 years old). Proc Natl Acad Sci USA 92: 6911–6914

    Article  PubMed  CAS  Google Scholar 

  34. Haidl S, Ivarsson S, Bjerre I et al (1992) Guillain-Barré syndrome after Chlamydia pneumoniae infection. N Engl J Med 326: 576–577

    PubMed  CAS  Google Scholar 

  35. Socan M, Veovic B, Kese D (1994) Chlamydia pneumoniae and meningoencephalitis. N Engl J Med 331: 406 (letter)

    Article  Google Scholar 

  36. Saikku P, Ruutu P, Leinonen M et al (1988) Acute lower respiratory tract infection associated with Chlamydia TWAR antibodies in Filipino children. J Infect Dis 158: 1095–1097

    Article  PubMed  CAS  Google Scholar 

  37. Grayston JT (1992) Infections caused by Chlamydia pneumoniae strain TWAR. Clin Infect Dis 15: 757–763

    Article  PubMed  CAS  Google Scholar 

  38. Marston BJ, Plouffe JF, File TM et al (1997) Incidence of community-acquired pneumonia requiring hospitalization. Arch Intern Med 157: 1709–1718

    Article  PubMed  CAS  Google Scholar 

  39. Saikku P (1991) Problems in diagnosis of Chlamydia pneumoniae infections. In: Vaheri A, Tilton RC, Balows A (eds) Rapid methods and automation in microbiology and immunology. Springer, Berlin Heidelberg New York, pp 309–313

    Chapter  Google Scholar 

  40. Gnarpe J, Gnarpe H, Sundelof BO (1991) Endemic prevalence of Chlamydia pneumoniaein subjectively healthy persons. Scand J Infect Dis 23: 387–388

    Article  PubMed  CAS  Google Scholar 

  41. Hyman CL, Roblin PM, Gaydos CA et al (1995) Prevalence of asymptomatic nasopharyngeal carriage of Chlamydia pneumoniae in subjectively healthy adults: assessment by polymerase chain reaction-enzyme immunoassay and culture. Clin Infect Dis 20: 1174–1178

    Article  PubMed  CAS  Google Scholar 

  42. von Hertzen L, Isohao R, Leinonen M et al (1996) Chlamydia pneumoniae antibodies in chronic obstructive pulmonary disease. Int J Epidemiol 25: 658–664

    Article  Google Scholar 

  43. Blasi F, Cosentini R, Damato S et al (1997) Chlamydia pneumoniae chronic infection increases the risk of bacterial colonization in chronic bronchitis. Am J Crit Care Respir Med 155: A592

    Google Scholar 

  44. Normann E, Gnarpe J, Gnarpe H et al (1998) Chlamydia pneumoniae in children attending day-care centers in Gävle, Sweden. Pediatr Infect Dis J 17: 474–478

    Article  PubMed  CAS  Google Scholar 

  45. Saikku P, Wang S-P, Kleemola M et al (1985) An epidemic of mild pneumonia due to an unusual Chlamydia psittaci strain. J Infect Dis 151: 832–839

    Article  PubMed  CAS  Google Scholar 

  46. Wang S-P, Grayston JT (1986) Microimmunofluorescence serological studies with TWAR organism. In: Oriel JD, Ridgway G, Schachter J, Taylor-Robinson D, Ward M (eds) Chlamydial infections. Cambridge University Press, Cambridge, UK, pp 329–332

    Google Scholar 

  47. Troy CJ, Peeling RW, Ellis AG et al (1997) Chlamydia pneumoniae as a new source of infectious outbreaks in nursing homes. JAMA 277: 1214–1218

    Article  PubMed  CAS  Google Scholar 

  48. Almirall J, Moratò I, Riera F et al (1993) Incidence of community-acquired pneumonia and Chlamydia pneumoniae infection: a prospective multicentre study. Eur Respir J 6: 14–18

    PubMed  CAS  Google Scholar 

  49. Cosentini R, Blasi F, Raccanelli R et al (1996) Severe community-acquired pneumonia: a possible role for Chlamydia pneumoniae. Respiration 63: 61–65

    Article  PubMed  CAS  Google Scholar 

  50. Pacheco A, Gonzales SJ, Aroncena C et al (1991) Community-acquired pneumonia caused by Chlamydia pneumoniae strain TWAR in chronic cardiopulmonary disease in the elderly. Respiration 58: 316–320

    Article  PubMed  CAS  Google Scholar 

  51. Riquelme R, Torres A, El-Ebiary M et al (1996) Community-acquired pneumonia in the elderly. Am J Respir Crit Care Med 154: 1450–1455

    PubMed  CAS  Google Scholar 

  52. Torres A, El-Ebiary M (1993) Relevance of Chlamydia TWAR in community-acquired respiratory infections. Eur Respir J 6: 7–8

    PubMed  CAS  Google Scholar 

  53. Emre U, Roblin PM, Gelling M et al (1994) The association of Chlamydia pneumoniaeinfection and reactive airway disease in children. Arch Pediatr Adolesc Med 148: 727–732

    Article  PubMed  CAS  Google Scholar 

  54. Cunningham AF, Johnston SL, Julious SA et al (1998) Chronic Chlamydia pneumoniae infection and asthma exacerbations in children. Eur Respir J 11: 345–349

    Article  PubMed  CAS  Google Scholar 

  55. von Hertzen L, Alakarppa H, Koskinen R et al (1997) Chlamydia pneumoniae infection in patients with chronic obstructive pulmonary disease. Epidemiol Infect 118: 155–164

    Article  Google Scholar 

  56. Boschini A, Smacchia C, Di Fine M et al (1996) Community acquired pneumonia in a cohort of former injection-drug users with and without human immunodeficiency virus infection: incidence etiologies and clinical aspects. Clin Infect Dis 23: 107–113

    Article  PubMed  CAS  Google Scholar 

  57. Dalhoff K, Maass M (1996) Chlamydia pneumoniae pneumonia in hospitalised patients. Clinical characteristics and diagnostic value of polymerase chain reaction detection in BAL. Chest 110: 351–356

    Article  PubMed  CAS  Google Scholar 

  58. Pesonen E, Siitonen O (1981) Acute myocardial infarction precipitated by infectious disease. Am Heart J 101: 512–513

    Article  PubMed  CAS  Google Scholar 

  59. Spodick DH, Flessas AP, Johnson MM (1984) Association of acute respiratory symptoms with the onset of acute myocardial infarction: prospective investigation of 150 consecutive patients and matched control patients. Am J Cardiol 53: 481–482

    Article  PubMed  CAS  Google Scholar 

  60. Blasi F, Denti F, Erba M et al (1996) Detection of Chlamydia pneumoniae and not of Helicobacter pylori in atherosclerotic plaques of aortic aneurysms. J Clin Microbiol 34: 2766–2769

    PubMed  CAS  Google Scholar 

  61. Ramirez JA, Ahkee S, Summersgill JT et al (1996) Isolation of Chlamydia pneumoniaefrom the coronary artery of a patient with coronary atherosclerosis. Ann Intern Med 125: 979–982

    PubMed  CAS  Google Scholar 

  62. Jackson LA, Campbell LA, Kuo C-C et al (1997) Isolation of Chlamydia pneumoniaefrom a carotid endoarterectomy specimen. J Infect Dis 176: 292–295

    Article  PubMed  CAS  Google Scholar 

  63. Blasi F, Cosentini R, Raccanelli R et al (1997) A possible association of Chlamydia pneumoniae infection and acute myocardial infarction in patients younger than 65 years of age. Chest 112: 309–312

    Article  PubMed  CAS  Google Scholar 

  64. Grayston JT, Kuo C-C, Coulson AS et al (1995) Chlamydia pneumoniae (TWAR) in atherosclerosis of the carotid artery. Circulation 92: 3397–3400

    PubMed  CAS  Google Scholar 

  65. Melnick SL, Shahar E, Folsom AR et al (1993) Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis Am J Med 945: 499–504

    Article  Google Scholar 

  66. Wimmer MLJ, Sandmannstrupp R, Saikku P et al (1996) Association of chlamydial infection with cerebrovascular disease. Stroke 27: 2207–2210

    Article  PubMed  CAS  Google Scholar 

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Blasi, F., Arosio, C., Cosentini, R. (1999). Chlamydia pneumoniae: Epidemiology. In: Allegra, L., Blasi, F. (eds) Chlamydia pneumoniae. Springer, Milano. https://doi.org/10.1007/978-88-470-2280-5_7

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  • DOI: https://doi.org/10.1007/978-88-470-2280-5_7

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0047-6

  • Online ISBN: 978-88-470-2280-5

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