Chlamydia pneumoniae Infections in Children
There has been considerable recent interest in the role of Chlamydia pneumoniae (CP) infection in both adults and children. The major interest with regard to children relates to its role in causing atypical pneumonia, and its possible role in the pathogenesis of bronchial, asthma. The prevalence of childhood asthma and other wheezing disorders has increased over the past few decades in most parts of the world . This illness causes substantial morbidity and mortality in children, and their management is associated with increasing healthcare costs . The etiology of asthma is complex, involving interactions between genetic susceptibility, allergen exposure and external aggravating factors such as air pollution, smoking and respiratory infections. The nature of the relationship between viral and bacterial infections in early childhood and the development of recurrent wheezing is controversial. The relationships between wheezing, coughing and respiratory distress and age, gender, atopy, viral infections, congenital structural abnormalities and baseline lung function (airway mechanics and hyperresponsiveness) are also dynamic and complex .
KeywordsChildhood Asthma Asthma Exacerbation Chlamydial Infection Atypical Pneumonia Chlamydia Pneumoniae
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