Open-Label Before-After Trials of Anti-Chlamydia pneumoniae Antibiotics in Asthma
At the time of writing, no randomized, controlled trials of anti-chlamydial antibiotics directed against asthma have been published. Such trials are underway, or are being planned, based upon (1) reported seroepidemiologic associations linking chlamydial infection to asthma (see the chapter,“Chlamydia pneumoniae: A New Possible Cause of Asthma”) and (2) published case reports [1, 2] and case series [3–5] indicating favorable results of open-label antibiotic administration to patients with asthma who also had culture-confirmed infection, seroreactivity, or both.
KeywordsAsthma Symptom Macrolide Antibiotic Chlamydial Infection Reactive Airway Disease Microbiologic Eradication
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- 3.Hahn DL (1995) Treatment of Chlamydia pneumoniae infection in adult asthma: a before-after trial. J Fam Pract 141: 345–351Google Scholar