Metabolic Disorders and Electrolyte Derangement during Hypoperfusion Syndrome

  • F. Schiraldi
  • A. R. Derosa
  • F. Paladino
Conference paper


Hypoperfusion could be defined as “a syndrome leading to widespread cellular hypoxia and vital organ dysfunction” [1], or “an inappropriate balance of substrate supply and demand at a cellular level” [2]; from a clinical point of view, whatever the cause, it is “a state in which reduction of effective tissue perfusion leads first to reversible, and then to irreversible cellular injury” [3]. Perhaps, after some intriguing insights about the subject, we should also include among the hypoperfusion syndromes any pathological O2 utilization at the cellular level, the so-called “dysoxia” [4, 5].


Fractional Excretion Lactic Acidosis Central Venous Blood Electrolyte Derangement Vital Organ Dysfunction 
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Copyright information

© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • F. Schiraldi
  • A. R. Derosa
  • F. Paladino

There are no affiliations available

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