Pharmacological Reversibility of Flow Limitation in COPD and Asthmatic Patients

  • C. Tantucci
Conference paper


Flow limitation (FL) describes a condition characterized by the inability to increase tidal expiratory flow under the prevailing conditions (Fig. 1). In all instances, FL represents the functional consequence of the complex interaction of three factors, namely bronchial caliber, breathing pattern and end-expiratory lung volume (EELV). Hence, any cause which decreases lung elastic recoil and/or increases airway resistance, enhances mean expiratory flow and reduces functional residual capacity (FRC) predisposes to FL.


Chronic Obstructive Pulmonary Disease Functional Residual Capacity Flow Limitation Inspiratory Capacity Dynamic Hyperinflation 


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© Springer-Verlag Italia, Milano 1998

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  • C. Tantucci

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