Clinical Assessment, Monitoring and Therapeutic Strategies for Septic Patients

  • B. Vallet
Conference paper


Sepsis is considered as the leading cause of death in non-coronary intensive care units (ICUs). Its early recognition and management should contribute to optimum therapeutic approach [1]. The clinical features of sepsis comprise those resulting from the primary insult, those pertaining to systemic inflammatory activation, and those resulting from end-organ dysfunction. There are two strands to current management: 1) antibiotic therapy and any means that can eradicate the infecting organism and thus halt its stimulation of the inflammatory response; 2) close monitoring and support of the patient in order to minimize the adverse effects of the inflammatory response on perfusion, oxygenation and organ function. However, and unfortunately, there is no regularly used current treatment aimed specifically at neutralising or inhibiting the endogenous inflammatory mediators.


Septic Shock Mean Arterial Pressure Septic Patient Multiple Organ Dysfunction Syndrome Simplify Acute Physiologic Score 
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© Springer-Verlag Italia, Milano 1998

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  • B. Vallet

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