Physiological Rationale to Prevent Ventilation-Induced Lung Injury

  • B. Lachmann
  • S. J. C. Verbrugge


Acute respiratory distress syndrome (ARDS) has become a well-recognized condition that can result from a number of different causes, e.g. sepsis, shock, pneumonia, trauma, liquid aspiration, hematologic disorders, smoke inhalation and many others [1]. Despite diverse etiologies of ARDS, the final common pathway results in damage of the alveolar epithelium and endothelium, which leads to high permeability edema.


Mechanical Ventilation Acute Respiratory Distress Syndrome Bacterial Translocation Adult Respiratory Distress Syndrome Acute Respiratory Distress Syndrome Patient 
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© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • B. Lachmann
  • S. J. C. Verbrugge

There are no affiliations available

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