Respiratory mechanics during general anaesthesia in healthy subjects

  • P. Pelosi
  • M. Resta
  • L. Brazzi
Part of the Topics in Anaesthesia and Critical Care book series (TIACC)


General anesthesia deeply influences the behavioral state, altering consciousness and sensation by the direct or indirect effects of various anesthetic drugs. However, these drugs may cause additional effects, sometimes undesirable on other organ systems. In particular, the effects on respiratory function seem to be significant. Although several studies investigated the effects of general anaesthesia on respiratory function, they were specifically performed in healthy young people, and did not include patients with different ages or anthropometric characteristics. Moreover, general anaesthesia may be performed in different positions or surgical conditions (i.e. during laparoscopy), which may further influence the respiratory function compared to the supine position. In this chapter we will discuss the effects of general anaesthesia on respiratory system mechanics in different categories of patients and surgical conditions, as well as the possible clinical implications of these findings and some therapeutic approaches.


Laparoscopic Cholecystectomy Respiratory System Lung Volume Functional Residual Capacity Respiratory Mechanic 
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© Springer-Verlag Italia, Milano 1999

Authors and Affiliations

  • P. Pelosi
  • M. Resta
  • L. Brazzi

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