Abstract
I am pleased to join Professor Gullo in welcoming all of you to the Sixth Organ Failure Academy Meeting here in Trieste, Italy, and to the program today, “An update on the pathophysiology of and potential therapy for sepsis and organ dysfunction”.
Inflammation in itself is not to be considered as a disease ... and in disease, where it can alter the diseased mode of action, it likewise leads to a cure; but where it cannot accomplish that solitaiy purpose .... it does mischief
John Hunter: A Treatise on the Blood, Inflammation, and Gunshot Wounds London, 1194 [1]
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Hunter J (1823) Treatise on the blood, inflammation, and gunshot wounds. 2nd edn James Webster, Philadelphia, p 205
Baue AE (1997) SIRS, MODS, MOF — Why no magic bullets? Arch Surg 132:1–5
Bone RC (1991) Sepsis, the sepsis syndrome, multi-organ failure: A plea for comparable definitions. Ann Intern Med 114:332–333
Baue AE (1992) The hoiTor autotoxicus and multiple-organ failure. Arch Surg 127:1451 -1462
Members of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee (1992) American College of Chest Physicians/Society of Critical Care Medicine consensus conference: definitions of sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20:864–874
Vincent JL (1993) Dear SIRS, I’m sorry to say that I don’t like you… Crit Care Med 25(2):372–374
Bone RC (1996) Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med 24(7): 1125–1128
Thomas L (1970) Adaptive aspects of inflammation, third symposium intemational inflammation club. Excerpta Medica 108. Upjohn Co, Kalamazoo
Ehrlich P, Morgenroth J (1901) Uber Hämolysins. Fünfte Mitheilung. Beri Klin Wochenschr 38:251–257
Baue AE (1994) Organ dysfunction (MODS) — Organ failure (MOF) and Therapeutic conundrums in injured and septic patients. A Gullo (ed) Organ Failure Academy. Foghazza, Milan, 2:9–39
Eun RJ, Wolff RJ (1976) Biology of endotoxin. Annual Rev Med 27:127–141
Ollodart RM, Hawthorne I, Attar S (1967) Studies in experimental endotoxemia in man. Am J Surg 113:599
Tracey KJ, Fung Y, Hesse KR et al (1987) Anticachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia. Nature 330:662–664
Echtenacher B, Falk W, Mannel DN, Krammer PH (1990) Requirement of endogenous tumor necrosis factor/cachectin for recovery from experimental peritonitis. J Immunol 145:3762–3766
Faist MD, Baue AE, Dittmer H, Herberer G (1983) Multiple organ failure in trauma patients. J Trauma 23(9):775–787
Sauaia A, Moore FA, Moore EE, Lezotte DC (1996) Early risk factors for postinjury multiple organ failure. Worid J Surg 20:392–400
Durham RM, Neunaber K, Mazuski JE et al (1996) The use of oxygen consumption and delivery as endpoints for resuscitation in critically ill patients. J Trauma 41(1):32
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer-Verlag Italia, Milano
About this paper
Cite this paper
Baue, A.E. (1998). The Complexities of Sepsis and Organ Dysfunction. In: Baue, A.E., Berlot, G., Gullo, A. (eds) Sepsis and Organ Dysfunction. Springer, Milano. https://doi.org/10.1007/978-88-470-2271-3_2
Download citation
DOI: https://doi.org/10.1007/978-88-470-2271-3_2
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-0297-5
Online ISBN: 978-88-470-2271-3
eBook Packages: Springer Book Archive