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History, Epidemiology and Clinical Evaluation of Rheumatoid Arthritis

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The Rheumatoid Hand

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Abstract

Rheumatoid arthritis (RA) is a chronic, autoimmune, inflammatory disease of the joints that affects subjects of all ages, with a predilection for women of post­menopausal age. Although the etiology of RA is still unknown, its pathogenesis is the result of multiple factors acting against the background of genetic predisposi­tion. Inflammation is probably triggered by nonspecific and as yet unknown infec­tious agents. The course of RA is usually chronic with alternating periods of exac­erbation and abatement. RA is not necessarily confined to the joints but can cause extraarticular manifestations that are frequently severe and sometimes life-threat­ening.

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Authors and Affiliations

  1. Department of Experimental Medicine, University of Genoa, Italy

    Giacomo Garlaschi & Enzo Silvestri

  2. MRI Division, Esaote Group, Genoa, Italy

    Luigi Satragno

  3. Department of Internal Medicine, Division of Rheumatology, University of Genoa, Italy

    Marco Amedeo Cimmino

Authors
  1. Giacomo Garlaschi
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  2. Enzo Silvestri
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  3. Luigi Satragno
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  4. Marco Amedeo Cimmino
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© 2002 Springer-Verlag Italia, Milano

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Garlaschi, G., Silvestri, E., Satragno, L., Cimmino, M.A. (2002). History, Epidemiology and Clinical Evaluation of Rheumatoid Arthritis. In: The Rheumatoid Hand. Springer, Milano. https://doi.org/10.1007/978-88-470-2266-9_1

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  • DOI: https://doi.org/10.1007/978-88-470-2266-9_1

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2268-3

  • Online ISBN: 978-88-470-2266-9

  • eBook Packages: Springer Book Archive

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