Genetic Predisposition in Asthma

  • C. Pomari
  • P. Turco


In 1921, Prausnitz demonstrated that the intradermal injection of serum from donors sensitive to a number of proteins caused skin sensitization to these proteins in the recipients [2]. In 1923, the serum factor responsible for this reaction was called “reagin” by the two American researchers, Coca and Cooke [5]. The latter also later coined the term “atopy” to indicate a number of clinical forms characterized by fever and bronchial asthma occurring in certain individuals when exposed to hay dust.


Mast Cell Allergic Rhinitis Allergy Clin Immunol Childhood Asthma Atopic Subject 
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© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • C. Pomari
    • 1
  • P. Turco
    • 1
  1. 1.Department of Lung PathophysiologyBussolengo General HospitalVeronaItaly

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