Abstract
In 1921, Prausnitz demonstrated that the intradermal injection of serum from donors sensitive to a number of proteins caused skin sensitization to these proteins in the recipients [2]. In 1923, the serum factor responsible for this reaction was called “reagin” by the two American researchers, Coca and Cooke [5]. The latter also later coined the term “atopy” to indicate a number of clinical forms characterized by fever and bronchial asthma occurring in certain individuals when exposed to hay dust.
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Pomari, C., Turco, P. (1993). Genetic Predisposition in Asthma. In: Allegra, L., Braga, P.C., Dal Negro, R. (eds) Methods in Asthmology. Springer, Milano. https://doi.org/10.1007/978-88-470-2263-8_4
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DOI: https://doi.org/10.1007/978-88-470-2263-8_4
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