Evaluation of In Vitro Data on Agents Acting on Respiratory Smooth Muscle Tone
When a chemical agent comes in contact (in different ways) with a biological structure there may be an interaction, with the final effect being a change from normal physiological function.
KeywordsIntrinsic Activity Theoretical Curf Negative Logarithm Competitive Antagonist Stimulant Drug
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- 1.Bonaccorsi A (1972) Sperimentazione farmacologica su organi isolati. Boringhieri, TorinoGoogle Scholar
- 2.Van Rossum JM (1963) Cumulative dose-response curves II. Technique for the making for dose-response curves in isolated organs and the evaluation of drug parameters. Arch Int Pharmacodyn 143: 299–330Google Scholar
- 4.Schild HO (1947) pA,, a new scale for the measurement of drug antagonism. Br J Pharmacol 2:189–207Google Scholar
- 5.Schild HO (1949) pAx and competitive drug antagonism. Br J Pharmacol 4: 277–280Google Scholar
- 6.Stephenson RP (1956) A modification of receptor theory. Br J Pharmacol 11: 379–394Google Scholar
- 7.Department of Pharmacology of the University of Edinburgh (1968) Pharmacological experiments on isolated preparations. Livingstone, EdinburghGoogle Scholar
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