Abstract
Three major pathogenetic components characterize bronchial asthma: (1) atopy, i.e., increased levels of IgE and increased degranulation of mast cells and basophils triggered by IgE-mediated or non-IgE-mediated stimuli; (2) allergic inflammation, which damages to varying extents the bronchial wall components (epithelium, vessels, submucosal glands, respiratory nerve endings, and smooth muscle); (3) bronchial hyperreactivity (BH) to physical, chemical, and allergic stimuli, which trigger bronchial obstruction by bronchospasm, vasodilation, mucosal edema, and mucous hypersecretion.
Keywords
- Force Vital Capacity
- Allergy Clin Immunol
- Total Lung Capacity
- Asthmatic Subject
- Geometric Standard Deviation
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1993 Springer-Verlag Berlin Heidelberg
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Del Bono, N., Del Bono, L. (1993). Mediators in Bronchial Provocation Tests. In: Allegra, L., Braga, P.C., Dal Negro, R. (eds) Methods in Asthmology. Springer, Milano. https://doi.org/10.1007/978-88-470-2263-8_18
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DOI: https://doi.org/10.1007/978-88-470-2263-8_18
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