Radiogas and Radioaerosol Production, Imaging, and Dosimetry in Asthmology
Using imaging techniques nuclear medicine studies the function of different organs and systems. When introduced in to a live organism, a radioactive chemical species with specific biological properties has a metabolic fate similar or identical to the same “cold” (nonradioactive) chemical agent. For example, the radioisotope of iodine, iodine-131 (131I), when administered orally in humans, is extracted from the intestine with the same efficiency as the cold iodine contained in food. Like dietary iodine, the radioactive 131I, after being concentrated from the blood in the thyroid and conjugated with thyroxine, also enters into the synthetic pathways of thyroid hormones. Due to these characteristics, a picomolar quantity of administered radioiodine allows “tracing” of the metabolic behavior of the total cold iodine contained in the thyroid. Therefore, it may be considered a tracer of thyroid metabolism of iodine.
KeywordsPerfusion Defect Lung Perfusion Single Photon Emission Tomography Lung Ventilation Geometrical Standard Deviation
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