The Wide Spectrum of Inflammatory Bowel Disease in Children
The inflammatory bowel diseases (IBD), Crohn’s Disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the intestines with a combined prevalence of 200–300 per 100 000 persons in the industrialized world . The peak frequency of new cases of CD in the pediatric population is during the mid to late teens with an age-specific incidence of 16 per 100 000 persons . It was suggested that a threefold rise in the incidence of CD occurred between 1968 to 1983, which further increased to 4.4 fold between 1968 and 1988 . In contrast, UC did not show an upward trend during the same period . A positive family history is the most consistent risk factor for children with IBD (odds ratio 5.6) .
KeywordsInflammatory Bowel Disease Ulcerative Colitis Sclerosing Cholangitis Juvenile Rheumatoid Arthritis Pyoderma Gangrenosum
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