What Is Clinical Relevance? - Well Controlled Experiments in Normal Animals as Compared to Clinical Studies in Diverse Sick Patients

  • A. E. Baue
Conference paper


There has been recent emphasis on performing animal studies that are clinically relevant. It has been said that some of the clinical trials of so-called “magic bullets” may not have been carried out if appropriate or relevant trials had been carried out beforehand in animals. Evidence-based or critical appraisal animal research has also been described [1]. This is an incredible expression because — what is research if it isn’t to provide evidence? It is now recommended also that we should practice evidence-based medicine [2].


Adult Respiratory Distress Syndrome Magic Bullet Yellow Fever Virus Perforated Diverticulitis Extracellular Acidosis 
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© Springer-Verlag Italia, Milano 1999

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  • A. E. Baue

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