Interest in the possible role of antioxidant vitamins in the prevention of heart disease has recently awakened in the medical and research community. Vitamin C in particular, however, has lagged behind lipid-soluble antioxidants, particularly vitamin E and carotenoids, in terms of the research conducted and the general impression of the strength of its role. Before reviewing the existing data, it may be useful to describe some of the reasons why there is a paucity of research and a generally unenthusiastic attitude in the medical and clinical trial community.
KeywordsVitamin Supplement Plasma Vitamin Plasma Ascorbic Acid High High Density Lipoprotein Plasma Ascorbate
Unable to display preview. Download preview PDF.
- 2.Simon JA (1992) Vitamin C and cardiovascular disease: a review. Am J Clin Nutr 11:107–125Google Scholar
- 3.Heine H, Norden C (1979) Vitamin C therapy in hyperlipoproteinemia. Int J Vitam Nutr Res 19:45–54Google Scholar
- 7.Block G, Mangels AR, Patterson BH et al (1997) Effect of body weight and prior depletion on blood ascorbate levels attained on several vitamin C dosages: a controlled diet study. Am J Clin Nutr (in press)Google Scholar
- 11.Stanton JL, Braitman LE, Riley AM, Khoo C, Smith JL (1982) Demographic, dietary, life style, and anthropometric correlates of blood pressure. Hypertension 4[Suppl III]:135–142Google Scholar
- 13.Koh ET, Chi MS (1980) Relationship of serum vitamin C and globulin fractions with anthropometric measurements in adults. Nutr Rep Int 21:537–549Google Scholar
- 14.Koh ET, Stewart T (1978) Interrelationship among the blood components and anthropometric measurements. Nutr Rep Int 18:539–548Google Scholar
- 21.Riemersma RA, Oliver M, Elton RA et al (1990) Plasma antioxidants and coronary heart disease: vitamins C and E and selenium. Eur J Clin Nutr 44:143–150Google Scholar
- 24.Cohen L, Feldman EB, Feldman DS, Harnes CG (1990) Dietary antioxidants and blood pressure. Am J Clin Nutr 50:511 (abstr)Google Scholar