Modulation of Cell Death by Oxidants and Antioxidants
Excessive oxidative stress kills cells. Until recently, however, the mode of cell death was largely ignored. Today, the study of cell death itself is one of the most rapidly growing areas in biomedical research. It is recognized that many compounds, rather than being directly cytotoxic, actually cause sublethal damage that triggers an innate suicide program in the cell. This process, termed apoptosis, is important during development, in maintaining tissue homeostasis, and also for removing damaged, infected, or potentially neoplastic cells.
KeywordsReactive Oxygen Species Reactive Oxygen Species Production Thiol Oxidation Excessive Oxidative Stress Maintain Tissue Homeostasis
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