Vitamin C pp 107-123 | Cite as

Recommended Vitamin C Intake: From Molecular Mechanisms to Clinical Application

  • M. Levine
  • S. C. Rumsey
  • Y. Wang
  • J. Park
  • R. Daruwala
  • N. Amano
Conference paper


The current recommended dietary allowance in the United States (U.S. RDA) for vitamin C (ascorbate) is 60 mg daily [1, 2]. Similar or lower values are used in other countries throughout the world except France, where the value is 80 mg daily. The U.S. RDA is based on prevention of clinical vitamin C deficiency, or scurvy, with a margin of safety. Safety is arbitrarily defined as prevention of scurvy for 1 month if vitamin C ingestion were to cease. Adequate vitamin C stores are also believed to occur at the dose which is at the threshold of urinary excretion of vitamin.


High Pressure Liquid Chromatography Recommended Dietary Allowance Dehydroascorbic Acid Chromaffin Granule Ascorbate Concentration 
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Copyright information

© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • M. Levine
    • 1
  • S. C. Rumsey
    • 1
  • Y. Wang
    • 1
  • J. Park
    • 1
  • R. Daruwala
    • 1
  • N. Amano
    • 1
  1. 1.Molecular and Clinical Nutrition Section, National Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthBethesdaUSA

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