Vitamin C pp 1-11 | Cite as

Antioxidants and Human Health

  • H. Sies
  • W. Stahl
Conference paper


Human health should be maintained from fertilization throughout life, and long-term exposure to potentially deleterious agents is obviously a factor in determining the function of the organism as well as the development of age-related degenerative diseases. Oxidants are potentially deleterious agents and, consequently, antioxidants play a role in the prevention of damage due to oxidants (for reviews on various aspects, see [1, 2]). Compounds known as antioxidants recently have been recognized as modulators of gene expression and of signal transduction pathways; these novel functions may not necessarily be based on the antioxidant properties, but rather on the function as ligands to regulatory proteins. The present contribution focuses first on oxidants, then on antioxidants; a previous review may be consulted [3].


Reactive Oxygen Species Lipid Peroxidation Nitric Oxide Singlet Oxygen Peroxyl Radical 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Italia, Milano 1998

Authors and Affiliations

  • H. Sies
    • 1
  • W. Stahl
    • 1
  1. 1.Institut für Physiologische Chemie I und Biologisch-Medizinisches ForschungszentrumHeinrich-Heine-Universität DüsseldorfDüsseldorfGermany

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