Placental transfer of pharmacological agents

  • E. Margaria
  • I. Castelletti
  • P. Petruzzelli
Part of the Topics in Anaesthesia and Critical Care book series (TIACC)


The placenta acts as an interface between maternal and fetal circulations. It transmits biological substances essential for fetal growth and development. Drugs cross the placenta by diffusing at varying rates, depending on their physical and chemical properties. Nonionized particles cross more rapidly than ions and small molecules more rapidly than large ones.


Maternal Plasma Placental Transfer Suxamethonium Chloride Fetal Plasma Uterine Blood Flow 
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Copyright information

© Springer Verlag Italia, Milano 1999

Authors and Affiliations

  • E. Margaria
  • I. Castelletti
  • P. Petruzzelli

There are no affiliations available

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