Imaging of Prostate Cancer

  • R. H. Oyen
Conference paper
Part of the Syllabus book series (SYLLABUS)


The popularity of imaging techniques to detect and to stage prostatic carcinomas has increased tremendously in the past decade. Nevertheless, most of the imaging techniques still have to compete with the digital rectal examination (DRE) and the serum concentration of prostate-specific antigen (PSA). There are two important reasons: the first is that the sensitivity of the imaging techniques now commonly used (i.e. transrectal ultrasonography, TRUS, and magnetic resonance imaging, MRI) lack sensitivity (a) to detect all cancers which originate in the prostate and (b) to stage the detected cancers accurately at a microscopic level. The second is that the imaging techniques lack specificity: many benign lesions closely resemble prostate carcinomas. For both reasons, biopsies are still required to obtain the final histological diagnosis.


Prostate Cancer Benign Prostatic Hyperplasia Radical Prostatectomy Prostatic Carcinoma Peripheral Zone 
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  1. 1.
    Renfer LG, Schow D, Thompson IM, Optenberg S (1995) Is ultrasound guidance necessary for transrectal prostate biopsy? J Urol 154:1390–1391PubMedCrossRefGoogle Scholar
  2. 2.
    Rifkin MD, Zerhouni EA, Gatsonis CA et al (1990) Comparison of MR imaging and US staging in staging early prostate cancer: results of a multi-institutional cooperative trial. N Engl J Med 323: 621–626PubMedCrossRefGoogle Scholar
  3. 3.
    Kelly IMG, Lees WR, Rickards D (1993) Prostate cancer and the role of color Doppler US. Radiology 189:153–156PubMedGoogle Scholar
  4. 4.
    Terris MK, McNeal JE, W Stamey TA (1992) Detection of clinically significant prostate cancer by transrectal ultrasound-guided systematic biopsies. J Urol 148: 829–832PubMedGoogle Scholar
  5. 5.
    Brendler CB (1995) Characteristics of prostate cancer found with early detection regimens. Urology [suppl 3A]: 71–76Google Scholar
  6. 6.
    Tempany CM, Zhou X, Zerhouni A et al (1994) Staging of prostate cancer: results of Radiology Diagnostic Oncology Group project: comparison of three MR imaging techniques. Radiology 192: 47–54PubMedGoogle Scholar
  7. 7.
    Hricak H, White S, Vigneron D et al (1994) Carcinoma of the prostate: MR imaging with pelvic phased array coils versus integrated endorectal-pelvic phased array coils. Radiology 193: 703–709PubMedGoogle Scholar
  8. 8.
    Schnall MD, Imai Y, Tomaszewski J, Pollack HM; Lenkinski RE, Kressel HY (1991) Prostate cancer: local staging with endorectal surface coil MR imaging. Radiology 178: 797–802PubMedGoogle Scholar
  9. 9.
    Schiebler ML, Schnall MD, Pollack HM et al (1993) Current role of MR imaging in staging of adenocarcinoma of the prostate. Radiology 189: 339–352PubMedGoogle Scholar
  10. 10.
    Hamper UM, Sheth S, Walsh PC, Holtz PM, Epstein JI (1991) Capsular transgression of prostatic carcinoma: evaluation with transrectal US with pathologic correlation. Radiology 178 (3): 791–795PubMedGoogle Scholar
  11. 11.
    Hering F, Rist M, Roth J et al (1990) Does microinvasion of the capsule and/or micrometastases in regional lymph nodes influence disease-free survival after radical prostatectomy? Br J Urol 66:177–181PubMedCrossRefGoogle Scholar
  12. 12.
    Vallancien G, Prapotnich D, Veillon B, Brisset JM, Andre-Bougaran J (1991) Seminal vesicle biopsies in the preoperative staging of prostatic cancer. Eur Urol 19:196–200PubMedGoogle Scholar
  13. 13.
    Stone NN, Stock RG, Unger P (1995) Indications for seminal vesicle biopsy and laparoscopic pelvic lymph node dissection in men with-localized carcinoma of the prostate. J Urol 154:1392–1396PubMedCrossRefGoogle Scholar
  14. 14.
    Wolf JS, Cher M, Dall’era M, Presti JC, Hricak H, Carroll PR (1995) The use and accuracy of cross-sectional imaging and fine needle aspiration cytology for detection of pelvic lymph node metastases before radical prostatectomy. J Urol 153: 993–999PubMedCrossRefGoogle Scholar
  15. 15.
    Oesterling JE (1995) Using prostate-specific antigen to eliminate unnecessary diagnostic tests: significant worldwide economic implications. Urology 46: 26–33PubMedCrossRefGoogle Scholar
  16. 16.
    Campbell SC, Klein EA, Levin HS, Piedmonte MR (1995) Open pelvic lymph node dissection for prostate cancer: a reassessment. Urology 46(3): 352–355PubMedCrossRefGoogle Scholar
  17. 17.
    Oyen RH, Van Poppel HP, Ameye FE, Van de Voorde WA, Baert AL, Baert LV (1994) Lymph node staging of localized prostatic carcinoma with CT and CT-guided fine needle aspiration biopsy: prospective study of 285 patients. Radiology 190: 315–321PubMedGoogle Scholar

Copyright information

© Springer-Verlag Italia, Milano 1996

Authors and Affiliations

  • R. H. Oyen
    • 1
  1. 1.Department of RadiologyUniversity Hospitals K.U.L.LeuvenBelgium

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