Abstract
On November 1, 1994, the SWORD (Survival With Oral D-sotalol) trial was terminated by the Steering Committee because of an excess mortality among the patients randomized to d-sotalol. Five years after the early termination of the Cardiac Arrhythmia Suppression Trial (CAST) for similar reasons, this event has caused further concern in the field of cardiac arrhythmias and electrophysiology and is raising questions about the availability of drugs that may reduce sudden cardiac death and also about the rationale and events that precede the initiation of large-scale clinical trials.
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© 1996 Springer-Verlag Italia, Milano
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Schwartz, P.J. (1996). What Have We Learned from the SWORD Trial? Can Potassium Channel Blockers Reduce Sudden Cardiac Death?. In: Raviele, A. (eds) Cardiac Arrhythmias 1995. Springer, Milano. https://doi.org/10.1007/978-88-470-2223-2_7
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DOI: https://doi.org/10.1007/978-88-470-2223-2_7
Publisher Name: Springer, Milano
Print ISBN: 978-3-540-75012-3
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