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Cardiac Arrhythmias 1995 pp 122–126Cite as

What Do We Know Today About the Outcome of Vasovagal Syncope?

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Abstract

Sudden loss of consciousness is a dramatic and often very frightening event for both patients and their families. While syncope has a wide differential diagnosis, the development of tilt table tests over the past 10 years has shown us that most patients in the community with syncope probably faint because of one of several presentations of vasovagal syncope. A good grasp of the prognosis of the patient is necessary in order to determine whether therapy need be attempted, and whether it is successful. There are a number of variants of vasovagal syncope, and each may have their own prognosis. Before we consider the prognosis of vasovagal syncope, we will first review some of the variants of this disorder and also review our current diagnostic maneuvers.

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References

  1. Pongiglione G, Fish FA, Strasburger JF, Benson W (1990) Heart rate and blood pressure response to upright tilt in young patients with unexplained syncope. J Am Coll Cardiol 16: 165–170

    Article  PubMed  CAS  Google Scholar 

  2. Perry JC, Garson A (1991) The child with recurrent syncope: autonomic function testing and beta-adrenergic hypersensitivity. J Am Coll Cardiol 17: 1168–1171

    Article  PubMed  CAS  Google Scholar 

  3. Thilenius OG, Quinones JA, Husayni TS, Novak J (1991) Tilt test for diagnosis of unexplained syncope in pediatric patients. Pediatrics 87: 334–338

    PubMed  CAS  Google Scholar 

  4. Balaji S, Oslizlok PC, Allen MC, McKay CA, Gillette PC (1994) Neurocardiogenic syncope in children with a normal heart. J Am Coll Cardiol 23: 779–785

    Article  PubMed  CAS  Google Scholar 

  5. Savage DD, Corwin L, McGee DL, Kannel WB, Wolf PA (1985) Epidemiologic features of isolated syncope: the Framingham study. Stroke 16: 626–629

    Article  PubMed  CAS  Google Scholar 

  6. Schwartz LS, Goldfischer J, Sprague GJ, Schwartz SP (1969) Syncope and sudden death in aortic stenosis. Am J Cardiol 23: 647–658

    Article  PubMed  CAS  Google Scholar 

  7. Grech ED, Ramsdale DR (1991) Exertional syncope in aortic stenosis: evidence to support inappropriate left ventricular baroreceptor response. Am Heart J 121: 603–606

    Article  PubMed  CAS  Google Scholar 

  8. Sheldon R (1994) Tilt table testing in the diagnosis and treatment of syncope. Cardiovasc Rev Rep 8–28

    Google Scholar 

  9. Kapoor W, Karpf M, Wieand S, Peterson J, Levey G (1983) A prospective evaluation and follow-up of patients with syncope. N Engl J Med 309: 197–204

    Article  PubMed  CAS  Google Scholar 

  10. Kushner JA, Kou WH, Kadish AH, Morady F (1989) Natural history of patients with unexplained syncope and a nondiagnostic electrophysiologic study. J Am Coll Cardiol 14: 391–396

    Article  PubMed  CAS  Google Scholar 

  11. Brignole M, Menozzi C, Gianfranchi L, Bottoni N, Lolli G (1992) The clinical and prognostic significance of the asystolic response during the head-up tilt test. Eur J Cardiac Pacing Electrophysiol 2: 109–113

    Google Scholar 

  12. Dhala A, Natale A, Sra J, Deshpande S, Blanck Z, Jazayeri MR, Akhtar M (1995) Relevance of asystole during head-up tilt testing. Am J Cardiol 75: 251–254

    Article  PubMed  CAS  Google Scholar 

  13. Sheldon R, Killam S (1992) Methodology of isoproterenol-tilt table testing in patients with syncope. J Am Coll Cardiol 19: 773–779

    Article  PubMed  CAS  Google Scholar 

  14. Brignole M, Menozzi C, Gianfranchi L, Lolli G, Bottoni N, Oddone D (1992) A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope. Am J Cardiol 70: 339–342

    Article  PubMed  CAS  Google Scholar 

  15. Morillo CA, Leitch JW, Yee R, Klein GJ (1993) A placebo-controlled trial of intravenous and oral disopyramide for prevention of neurally mediated syncope induced by head-up tilt. J Am Coll Cardiol 22: 1843–1848

    Article  PubMed  CAS  Google Scholar 

  16. Natale A, Biehl M, Banks B, Maglio C, Krebs A, Budziszewski

    Google Scholar 

  17. M, Koch K, Sra J (1994) Recurrence of neurocardiogenic syncope without therapeutic interventions. Circulation 90: 1–54 (abstr)

    Google Scholar 

  18. Morillo CA, Zandri S, Klein GJ, Yee R (1994) Neurally mediated syncope: long-term follow-up of patients with and without pharmacological therapy. Circulation 90: 1–54 (abstr)

    Google Scholar 

  19. Sheldon RS, Rose S, Flanagan P, Koshman ML, Killam S (1994) Multivariate predictors of syncope recurrence in drug-free patients following a positive tilt table test. Circulation 90: I55 (abstr)

    Google Scholar 

  20. Menozzi C, Brignole M, Lolli G, Bottoni N, Oddone D, Gian-franchi L, Gaggioli G (1993) Follow-up of asystolic episodes in patients with cardioinhibitory, neurally mediated syncope and VVI pacemaker. Am J Cardiol 72: 1152–1155

    Article  PubMed  CAS  Google Scholar 

  21. Benditt DG, Petersen M, Lurie KG, Grubb BP, Sutton R (1995) Cardiac pacing for prevention of recurrent vasovagal syncope. Ann Intern Med 122: 204–209

    PubMed  CAS  Google Scholar 

  22. Almquist A, Goldenberg IF, Milstein S et al. (1989) Provocation of bradycardia and hypotension by isoproterenol and upright posture in patients with unexplained syncope. N Engl J Med 320: 346–351

    Article  PubMed  CAS  Google Scholar 

  23. Strieper MJ, Campbell RM (1993) Efficacy of alpha-adrenergic agonist therapy for prevention of pediatric neurocardiogenic syncope. J Am Coll Cardiol 22: 594–597

    Article  PubMed  CAS  Google Scholar 

  24. Milstein S, Buetikofer J, Dunnigan A, Benditt DG, Gornick C, Reyes WJ (1990) Usefulness of disopyramide for prevention of upright tilt-induced hypotension-bradycardia. Am J Cardiol 65: 1339–1344

    Article  PubMed  CAS  Google Scholar 

  25. Grubb BP, Samoil D, Kosinski D, Kip K, Brewster P (1994) Use of sertraline hydrochloride in the treatment of refractory neurocardiogenic syncope in children and adolescents. J Am Coll Cardiol 24: 490–494.

    Article  PubMed  CAS  Google Scholar 

  26. Grubb BP, Temesy-Armos P, Hahn H, Elliott L (1991) Utility of upright tilt-table testing in the evaluation and management of syncope of unknown origin. Am J Med 90: 6–10

    Article  PubMed  CAS  Google Scholar 

  27. Linzer M, Pontinen M, Gold DT, Divine GW, Felder A, Brooks WB (1991) Impairment of physical and psychosocial function in recurrent syncope. J Clin Epidemiol 44: 10371043

    Google Scholar 

  28. Linzer M, Gold DT, Pontinen M, Divine GW, Felder A, Brooks WB (1994) Recurrent syncope as a chronic disease: preliminary validation of a disease-specific measure of functional impairment. J Gen Intern Med 9: 181–186

    Article  PubMed  CAS  Google Scholar 

  29. Pritchett ELC, Lee KL (1988) Designing clinical trials for paroxysmal atrial tachycardia and other paroxysmal arrhythmias. J Clin Epidemiol 41: 851–858

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Cardiovascular Research Group, University of Calgary, Canada

    R. S. Sheldon

  2. Division of Cardiology, Calgary General Hospital, Calgary, Canada

    R. S. Sheldon

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  1. R. S. Sheldon
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Editors and Affiliations

  1. Divisione di Cardiologia, Ospedale Umberto I, Via Circonvallazione 50, I-30174, Venezia Mestre, Italy

    Antonio Raviele MD

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© 1996 Springer-Verlag Italia, Milano

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Sheldon, R.S. (1996). What Do We Know Today About the Outcome of Vasovagal Syncope?. In: Raviele, A. (eds) Cardiac Arrhythmias 1995. Springer, Milano. https://doi.org/10.1007/978-88-470-2223-2_21

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  • DOI: https://doi.org/10.1007/978-88-470-2223-2_21

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-3-540-75012-3

  • Online ISBN: 978-88-470-2223-2

  • eBook Packages: Springer Book Archive

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