Advertisement

Drug-Induced Pancreatitis

  • C. B. Kölbel
  • M. V. Singer
Conference paper

Abstract

Since 1959, when the first report on drug-induced pancreatitis was published by Johnston and Cornish [58], at least 50 different drugs have been implicated as possible but rare causes of pancreatitis. A convincing causal relationship has been established for only a small number of these drugs while the pathogenesis of this type of pancreatitis remains almost completely elusive. This chapter gives an overview on different aspects of drug-induced pancreatitis. As generally accepted, three categories of drugs are discussed inasfar as their causal relationship with the development of pancreatitis is definite, probable, or possible [73].

Keywords

Acute Pancreatitis Valproic Acid Cytosine Arabinoside Ethacrynic Acid Acute Hemorrhagic Pancreatitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Alberti-Fior JJ, Hernández ME, Ferrer JP, Howell S, Jeffers L (1989) Fulminant liver failure and pancreatitis associated with the use of sulfamethoxazole-trimethoprim. Am J Gastroenterol 84: 1577–1579Google Scholar
  2. 2.
    Altman AJ, Dinndorf P, Quinn JJ (1982) Acute pancreatitis in association with cytosine arabinoside therapy. Cancer 49: 1386CrossRefGoogle Scholar
  3. 3.
    Anderson PE, Ellis GG Jr, Austin SM (1991) Case report: metolazone-associated hypercalcemia and acute pancreatitis. Am J Med Sci 302: 235–237PubMedCrossRefGoogle Scholar
  4. 4.
    Antonow DR (1986) Acute pancreatitis associated with trimethoprim-sulfamethoxazole. Ann Intern Med 104: 363–365PubMedGoogle Scholar
  5. 5.
    Arnold F, Doule PJ, Bell G (1978) Acute pancreatitis in a patient treated with Cimetidine. Lancet i: 382–383CrossRefGoogle Scholar
  6. 6.
    Baar HS, Wolff OH (1957) Pancreatic necrosis in cortisone-treated children. Lancet 1: 812–815CrossRefGoogle Scholar
  7. 7.
    Bank S, Marks IN (1970) Hyperlipaemic pancreatitis and the pill. Postgrad Med J 46: 576–588PubMedCrossRefGoogle Scholar
  8. 8.
    Bank L, Wright JP (1984) 6-Mercaptopurine-related pancreatitis in 2 patients with inflammatory bowel disease. Dig Dis Sci 29: 357–359PubMedCrossRefGoogle Scholar
  9. 9.
    Bess MA, Edis AJ, van Heerden JA (1980) Hyperparathyroidism and pancreatitis: chance or a causal association? JAMA 243: 246–247PubMedCrossRefGoogle Scholar
  10. 10.
    Birchfield GR, Ward JH, Redman BG, Flaherty L, Samlowski WE (1990) Acute pancreatitis associated with high-dose interleukin-2 immunotherapy for malignant melanoma. West J Med 152: 714–716PubMedGoogle Scholar
  11. 11.
    Block MB, Genant HK, Kirsner JB (1970) Pancreatitis as an adverse reaction to salicylazosulfapyridine. N Engl J Med 282: 380–382PubMedCrossRefGoogle Scholar
  12. 12.
    Bourke JB, Langman MJS (1980) Do diuretics cause pancreatitis? [letter] Gastroenterology 79 : 774PubMedGoogle Scholar
  13. 13.
    Brazer SR, Medoff JR (1988) Sulfonamide-induced pancreatitis. Pancreas 3: 583–586PubMedCrossRefGoogle Scholar
  14. 14.
    Bristol-Myers Squibb Pharmaceutical Research Institute (1991) ddI-Quarterly Safety Summary.Google Scholar
  15. 15.
    Buchanan N, Cane RD (1977) Furosemide-induced pancreatitis. Br Med J 2:1417PubMedCrossRefGoogle Scholar
  16. 16.
    Buckspan R, Woltering E, Waterhouse G (1984) Pancreatitis induced by intravenous infusion of a fat emulsion in an alcoholic patient. South Med J 77: 251–252PubMedCrossRefGoogle Scholar
  17. 17.
    Bunin N, Meyer WH, Christensen M, Pratt CB (1985) Pancreatitis following cisplatin: a case report [letter]. Cancer Treat Rep 69: 236–237PubMedGoogle Scholar
  18. 18.
    Cabooter M, Elewaut A, Barbier F (1981) Salicylate-induced pancreatitis. Gastroenterology 80 : 214–215PubMedGoogle Scholar
  19. 19.
    Call T, Malarkey WB, Thomas FB (1977) Acute pancreatitis secondary to furo-semide with associated hyperlipidemia. Am J Dig Dis 22: 835–838PubMedCrossRefGoogle Scholar
  20. 20.
    Calvo DB, Patt YZ, Wallace S, Chuang VP, Benjamin RS, Pritchard JD, Hersh EM, Bodey GP, Mavligit GM (1980) Phase I-II trial of percutaneous intraarterial cis-diammine dichloroplatinum (II) for regionally confined malignancy. Cancer 45: 1278–1238PubMedCrossRefGoogle Scholar
  21. 21.
    Carone F, Liebon A (1957) Acute pancreatic lesion in patients treated with A.C.T.H. and adrenal corticoids. N Engl J Med 257: 690–697PubMedCrossRefGoogle Scholar
  22. 22.
    Chevalier X, Awada H, Baetz A, Amor B (1990) Danazol induced pancreatitis and hepatitis. Clin Rheumatol 9: 239–241PubMedCrossRefGoogle Scholar
  23. 23.
    Colon R, Frazier OH, Kahan BD, Radovancevic B, Duncan JM, Lorber MI, Van Buren CT (1988) Complications in cardiac transplant patients requiring general surgery. Sugery 103: 32–38Google Scholar
  24. 24.
    Connolly KJ, Allan JD, Fitch H, Jackson-Pope L, McLaren C, Canetta R, Groopman JE (1991) Phase I study of 2′, 3′-dideoxyinosine administered orally twice daily to patients with AIDS or AIDS-related complex and hematologic intolerance to zidovudine. Am J Med 91: 471–478PubMedCrossRefGoogle Scholar
  25. 25.
    Cooley TP, Kunches LM, Saunders CA, Ritter JK, Perkins CJ, McLaren C, McCaffrey RP, Liebman HA (1990) Once-daily administration of 2′, 3′-dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Results of a phase I trial. N Engl J Med 322: 1340–1345PubMedCrossRefGoogle Scholar
  26. 26.
    Corey WA, Doebbeling BN, DeJong KJ, Britigan BE (1991) Metronidazole-induced acute pancreatitis. Rev Infect Dis 13: 1213–1215PubMedCrossRefGoogle Scholar
  27. 27.
    Cornish AL, McClellan JT, Johnston DH (1961) Effects of chlorothiazide on the pancreas. N Engl J Med 265: 673–675PubMedCrossRefGoogle Scholar
  28. 28.
    Das KM, Eastwood MA, McManus JP, Sircus W (1973) Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. N Engl J Med 289: 491–495PubMedCrossRefGoogle Scholar
  29. 29.
    Davidhoff F, Tishler S, Rosoff C (1973) Marked hyperlipemia and pancreatitis associated with oral contraceptive therapy. N Engl J Med 289: 552–555CrossRefGoogle Scholar
  30. 30.
    Deprez P, Descamps C, Fiasse R (1989) Pancreatitis induced by 5-aminosalicylic acid [letter]. Lancet 2 (8660): 445–446PubMedCrossRefGoogle Scholar
  31. 31.
    Dolin R, Lambert JS, Morse GD, Reichman RC, Plank CS, Reid J, Knupp C, McLaren C, Pettinelli C (1990) 2′, 3′-Dideoxyinosine in patients with AIDS or AIDS-related complex. Rev Infect Dis 12 (Suppl 5): S 540–549Google Scholar
  32. 32.
    Donnelly H, Bernard EM, Rothkotter H, Gold JWM, Armstrong D (1988) Distribution of pentamidine in patients with AIDS. J Infect Dis 157: 985–989PubMedCrossRefGoogle Scholar
  33. 33.
    Eckardt VF, Kanzler G, Rieder H, Ewe K (1991) 5-Aminosalicylsäure-assoziierte Pankreatitis. Dtsch Med Wochensch 116: 540–542CrossRefGoogle Scholar
  34. 34.
    Eckhauser ML, Dokler M, Imbembo AL (1987) Diuretic-associated pancreatitis: a collective review and illustrative cases. Am J Gastroenterol 82: 865–870PubMedGoogle Scholar
  35. 35.
    Eden OB, Shaw MP, Lilleyman JS, Richards S (1990) Non-randomised study comparing toxicity of Escherichia coli and Erwinia asparaginase in children with leukaemia. Med Pediatr Oncol 18: 497–502PubMedCrossRefGoogle Scholar
  36. 36.
    Eisemann AD, Becker NJ, Miner PB Jr, Fleming J (1989) Pancreatitis and gold treatment of rheumatoid arthritis [letter]. Ann Intern Med 111: 860–861PubMedGoogle Scholar
  37. 37.
    Elmore M, Rogge J (1981) Tetracycline-induced pancreatitis. Gastroenterology 81: 1134–1136PubMedGoogle Scholar
  38. 38.
    Evans DB, Slapak M (1975) Pancreatitis in the hard water syndrome. Br Med J 3: 748PubMedCrossRefGoogle Scholar
  39. 39.
    Faintuch J, Mott CB, Machado MC (1985) Pancreatitis and pancreatic necrosis during sulfasalazine therapy. Int Surg 70: 271–272PubMedGoogle Scholar
  40. 40.
    Fernández JA, Rosenberg JC (1976) Post-transplantation pancreatitis. Surg Gynecol Obstet 143: 795–798PubMedGoogle Scholar
  41. 41.
    Fiorentini MT, Fracchia M, Galatola G, Barlotta A, de la Pierre M (1990) Acute pancreatitis during oral 5-aminosalicylic acid therapy. Dig Dis Sci 35: 1180–1182PubMedCrossRefGoogle Scholar
  42. 42.
    Foster ME, Powell DEB (1975) Pancreatitis, multiple infarcts and oral contraception. Postgrad Med J 51: 667–669PubMedCrossRefGoogle Scholar
  43. 43.
    Frick TW, Fryd DS, Goodale RL, Simmons RL, Sutherland DE, Najarian JS (1991) Lack of association between azathioprine and acute pancreatitis in renal transplantation patients [letter]. Lancet 337: 251–252PubMedCrossRefGoogle Scholar
  44. 44.
    Fuchs JE Jr, Keith MR, Galanos AN (1989) Probable metolazone-induced pancreatitis [letter]. DICP 23: 711PubMedGoogle Scholar
  45. 45.
    Glueck CJ, Scheel D, Fishback J, Steiner P (1972) Estrogen-induced pancreatitis in patients with previously covert familialtype V hyperlipoproteinemia. Metabolism 21: 657–666PubMedCrossRefGoogle Scholar
  46. 46.
    Goldstein J, Laskin DA, Ginsberg GH (1980) Sulindac associated with pancreatitis (letter). Ann Intern Med 93: 151PubMedGoogle Scholar
  47. 47.
    Grimaud JC, Maillot A, Bremondy A, Thervet L, Salducci J (1989) Faut-il toujours accuser la sulfapyridine? A propos d’un cas de pancréatite aiguë induite par la mésalazine. Gastroent Clin Biol 13: 432PubMedGoogle Scholar
  48. 48.
    Guillaume P, Grandjean E, Male PJ (1984) Azathioprine-associated acute pancreatitis in the course of chronic active hepatitis. Dig Dis Sci 29: 78–79PubMedCrossRefGoogle Scholar
  49. 49.
    Haber CJ, Meltzer SJ, Present DH, Korelitz BI (1986) Nature and course of pancreatitis caused by 6-mercaptopurine in the treatment of inflammatory bowel disease. Gastroenterology 91: 982–986PubMedGoogle Scholar
  50. 50.
    Herrmann R, Shaw RG, Fone DJ (1990) Ranitidine-associated recurrent acute pancreatitis. Aust N Z J Med 20: 243–244PubMedCrossRefGoogle Scholar
  51. 51.
    Heuser E, Lieberman E, Donnell GN, Landing BH (1967) Subcutaneous fat necrosis with acute hemorrhagic pancreatitis: a case in a child with steroid-resistant nephrosis treated with 6-mercaptopurine. California Med 106: 58–63PubMedGoogle Scholar
  52. 52.
    Hirschel B, Vanhems P (1991) Anti-retrovirale Therapie in der Schweiz 1991. Schw Med Wschr 121: 1187–1193Google Scholar
  53. 53.
    Hochgelerent EL, Davis DS (1974) Acute pancreatitis secondary to calcium infusion in a dialysis patient. Arch Surg 108: 218–219PubMedCrossRefGoogle Scholar
  54. 54.
    Holland SD, Williamson HE (1984) Acute effects of high-ceiling diuretics on pancreatic blood flow and function. J Pharmacol Exp Ther 229: 440–446PubMedGoogle Scholar
  55. 55.
    Isaacs KL, Murphy D (1990) Pancreatitis after rectal administration of 5-aminosalicylic acid. J Clin Gastroenterol 12: 198–199PubMedCrossRefGoogle Scholar
  56. 56.
    Izsak ME, Shike M, Roulet M, Jeejeebhoy KN (1980) Pancreatitis in association with hypercalcemia in patients receiving total parenteral nutrition. Gastroenterology 79 : 555–558PubMedGoogle Scholar
  57. 57.
    Joffe S, Lee FK (1978) Acute pancreatitis after Cimetidine administration in experimental duodenal ulcers. Lancet 1: 383PubMedCrossRefGoogle Scholar
  58. 58.
    Johnston DH, Cornish AL (1959) Acute pancreatitis in patients receiving chlorothiazide. JAMA 170: 2054–2056CrossRefGoogle Scholar
  59. 59.
    Jones MF, Caldwell JR (1962) Acute hemorrhagic pancreatitis associated with the administration of chlorthalidone. N Engl J Med 267: 1029–1031CrossRefGoogle Scholar
  60. 60.
    Jones PE, Oelbaum MH (1975) Furosemide-induced pancreatitis. Br Med J 1: 133–134PubMedCrossRefGoogle Scholar
  61. 61.
    Kawanishi H, Rudolph E, Bull FE (1973) Azathioprine-induced acute pancreatitis. N Engl J Med 289: 357PubMedCrossRefGoogle Scholar
  62. 62.
    Kayemba Kay’s Kabangu S, Bovier Lapierre M, Jalaguier E (1991) Acute pancreatitis and valproic acid. Pédiatrie 46: 839–843 (in French)PubMedGoogle Scholar
  63. 63.
    Klatt EC (1992) Pathology of pentamidine-induced pancreatitis. Arch Pathol Lab Med 116: 162–164PubMedGoogle Scholar
  64. 64.
    Klein SM, Khan MA (1983) Hepatitis, toxic epidermal necrolysis and pancreatitis in association with sulindac therapy. J Rheumatol 10: 512–513PubMedGoogle Scholar
  65. 65.
    Kokkinakis DM, Scarpelli DG, Rao MS, Hollenberg PF (1983) Metabolism of the pancreatic carcinogens N-nitroso-2,6-dimethylmorpholine and N-nitrosobis(2-oxopropyl)amine by microsomes and cytosol of hamster pancreas and liver. Cancer Res 43: 5761–5767PubMedGoogle Scholar
  66. 66.
    Kunelis CT, Peters JL, Edmondson HA (1965) Fatty liver of pregnancy and its relationship to tetracycline therapy. Am J Med 38: 359–377PubMedCrossRefGoogle Scholar
  67. 67.
    Lambert JS, Seidlin M, Reichman RC, Plank CS, Laverty M, Morse GD, Knupp C, McLaren C, Pettinelli C, Valentine FT, Dolin R (1990) 2′, 3′-Dideoxyinosine (ddI) in patients with the acquired immunodeficiency syndrome or AIDS-related complex. A phase I trial. N Engl J Med 322: 1333–1340PubMedCrossRefGoogle Scholar
  68. 68.
    Lashner BA, Kirsner JB, Hanauer SB (1986) Acute pancreatitis associated with high-concentration lipid emulsion during total parenteral nutrition therapy for Crohn’s disease. Gastroenterology 90: 1039–1041PubMedGoogle Scholar
  69. 69.
    Leeson PM, Fourman P (1966) Acute pancreatitis from vitamin D poisoning in a patient with parathyroid deficiency. Lancet 1: 1185–1186CrossRefGoogle Scholar
  70. 70.
    Levine RA, McGuire RF (1988) Corticosteroid-induced pancreatitis: a case report demonstrating recurrence with rechallenge. Am J Gastroenterol 83: 1161–1164PubMedGoogle Scholar
  71. 71.
    Lilly EL (1981) Pancreatitis after administration of sulindac (letter). JAMA 246: 2680PubMedCrossRefGoogle Scholar
  72. 72.
    Lorber MI, Van Buren CT, Flechner SM, Williams C, Kahan BD (1987) Hepatobiliary and pancreatic complications of cyclosporine therapy in 466 renal transplant recipients. Transplantation 43: 35–40PubMedCrossRefGoogle Scholar
  73. 73.
    Mallory A, Kern F (1980) Drug-induced pancreatitis: a critical review Gastroenterology 78 : 813–820PubMedGoogle Scholar
  74. 74.
    Mallory A, Kern F (1980) Drug-induced pancreatitis. Baillieres Clin Gastroenterol 2:293–307CrossRefGoogle Scholar
  75. 75.
    Maxson CJ, Greenfield SM, Turner JL (1992) Acute pancreatitis as a common complication of 2′, 3′-dideoxyinosine therapy in the acquired immunodeficiency syndrome. Am J Gastroenterol 87: 708–713PubMedGoogle Scholar
  76. 76.
    McCormick PA, O’Donoghue D, Brennan N (1985) Diphenoxylate and pancreatitis [letter]. Lancet 1 (8431): 752PubMedCrossRefGoogle Scholar
  77. 77.
    Memon AN (1982) Pancreatitis and sulindac (letter). Ann Intern Med 97: 139PubMedGoogle Scholar
  78. 78.
    Meyers S (1988) Disodium azodisalicylate and sulfasalazine [letter]. Am J Gastroenterol 83 : 1187PubMedGoogle Scholar
  79. 79.
    Miller TL, Winter HS, Luginbuhl LM, Orav EJ, Mcintosh K (1992) Pancreatitis in pediatric human immunodeficiency virus infection. J Pediatr 120: 223–227PubMedCrossRefGoogle Scholar
  80. 80.
    Moir DC (1978) Drug-associated acute pancreatitis. Lancet ii: 369–370CrossRefGoogle Scholar
  81. 81.
    Murphey SA, Josephs AS (1981) Acute pancreatitis associated with pentamidine therapy. Arch Intern Med 141: 56–58PubMedCrossRefGoogle Scholar
  82. 82.
    Murphy RL, Noskin GA, Ehrenpreis ED (1990) Acute pancreatitis associated with aerosolized pentamidine. Am J Med 88: 53N-56NPubMedCrossRefGoogle Scholar
  83. 83.
    Nelis GF (1983) Nitrofurantoin-induced pancreatitis: report of a case. Gastroenterology 84: 1032–1034PubMedGoogle Scholar
  84. 84.
    Nguyen DL, Wilson DA, Engelman ED, Sexauer CL, Nitschke R (1987) Serial sonograms to detect pancreatitis in children receiving L-asparaginase. South Med J 80: 1133–1136PubMedCrossRefGoogle Scholar
  85. 85.
    Nicolau DP, Mengedoht DE, Kline JJ (1991) Tetracycline-induced pancreatitis. Am J Gastroenterol 86: 1669–1671PubMedGoogle Scholar
  86. 86.
    Nogueira JR, Freedman MA (1972) Acute pancreatitis as a complication of Imuran therapy in regional enteritis. Gastroenterology 62: 1040–1041PubMedGoogle Scholar
  87. 87.
    Noseworthy J, Colodny AH, Eraklis AJ (1983) Pancreatitis and intravenous fat: an association in patients with inflammatory bowel disease. J Ped Surg 18: 269–272CrossRefGoogle Scholar
  88. 88.
    Nott DM, de Sousa BA (1989) Suspected cimetidine-induced acute pancreatitis. Br J Clin Parct 43: 264–265Google Scholar
  89. 89.
    Ober WB, LeCompte PM (1955) Acute fatty metamorphosis of the liver associated with pregnancy. Am J Med 19: 743–758PubMedCrossRefGoogle Scholar
  90. 90.
    O’Neil MG, Selub SE, Hak LJ (1991) Pancreatitis during pentamidine therapy in patients with AIDS. Clin Pharm 10: 56–59PubMedGoogle Scholar
  91. 91.
    Oppenheimer EH, Boitnott JK (1960) Pancreatitis in children following adrenal corticosteroid therapy. Bull Johns Hosp 107: 297–306Google Scholar
  92. 92.
    Paloyan D, Levin B, Simonowitz D (1977) Azathioprine-associated acute pancreatitis. Am J Dig Dis 22: 839–840PubMedCrossRefGoogle Scholar
  93. 93.
    Pauwels A, Eliaszewicz M, Larrey D, Lacassin F, Poirier JM, Meyohas MC, Frottier J (1990) Pentamidine-induced acute pancreatitis in a patient with AIDS. J Clin Gastroenterol 12: 457–459PubMedCrossRefGoogle Scholar
  94. 94.
    Picon M, Causse X, Gelas P, Retornaz G, Trepo C, Bouletreau P (1991) Hépatite aiguë sévère à la pentamidine au cours du traitement d’une pneumocystose liée au SIDA (letter). Gastroenterol Clin Biol 15: 463–464PubMedGoogle Scholar
  95. 95.
    Plotnick BH, Cohen I, Tsang T, Cullinane T (1985) Metronidazole-induced pancreatitis. Ann Intern Med 103: 891–892PubMedGoogle Scholar
  96. 96.
    Pluhar W (1989) Ein Fall möglicher Lovostatin-induzierter Pankreatitis bei gleichzeitigem Gilbert-Syndrom. Wien Klin Wchschr 101: 551–554Google Scholar
  97. 97.
    Poldermans D, van Blankenstein M (1988) Pancreatitis induced by disodium azodisalicylate. Am J Gastroenterol 83: 578–580PubMedGoogle Scholar
  98. 98.
    Present DH, Meltzer SJ, Krumholz MP, Wolke A, Korelitz BI (1989) 6-Mercaptopurine in the management of inflammatory bowel disease : short- and long-term toxicity. Ann Intern Med 111 : 641–649PubMedGoogle Scholar
  99. 99.
    Prevost X, Myara I, Cosson C, Duboust A, Moatti N (1988) Asymptomatic hyperamylasemia after cyclosporine therapy in patients with renal transplants. Transplant Proc 20: 555–558PubMedGoogle Scholar
  100. 100.
    Przepiorka D, Shapiro S, Schwinghammer TL, Bloom EJ, Rosenfeld CS, Shad-duck RK, Venkataramanan R (1991) Cyclosporine and methylprednisolone after allogeneic marrow transplantation: association between low cyclosprine concentration and risk of acute graft-versus-host disease. Bone Marrow Transplant 7: 461–465PubMedGoogle Scholar
  101. 101.
    Reimenschneider TA, Wilson JF, Vernier RL (1968) Glucocorticoid-induced pancreatitis in children. Pediatrics 41: 428–437Google Scholar
  102. 102.
    Ried M, Gibbons S, Kwok D et al. (1983) Cyelosporine levels in human tissues of patients treated for one week to one year. Transplant Proc 15 (suppl 1) : 2434Google Scholar
  103. 103.
    Romero Castro R, Jiménez Saenz M, Pellicer Bautista FJ, Dommguez Palomo S, Herrerias Gutiérrez JM (1991) Pancreatitis acuda por acido 5-aminosalicilico. Rev Esp Enferai Dig 79: 219–221Google Scholar
  104. 104.
    Rominger JM, Gutiérrez JG, Curtis D, Chey WY (1978) Methyldopa-induced pancreatitis. Am J Dig Dis 23: 756–758PubMedCrossRefGoogle Scholar
  105. 105.
    Rozencweig M, McLaren C, Beltangady M, Ritter J, Canetta R, Schacter L, Kelley S, Nicaise C, Smaldone L, Dunkle L et al. (1990) Overview of phase I trials of 2′, 3′-dideoxyinosine (ddI) conducted on adult patients. Rev Infect Dis 12 (Suppl 5) S570-S575PubMedCrossRefGoogle Scholar
  106. 106.
    Sachedina B, Saibil F, Cohen LB, Whittey J (1989) Acute pancreatitis due to 5-aminosalicylate. Ann Intern Med 110: 490–492PubMedGoogle Scholar
  107. 107.
    Salmeron S, Petitpretz P, Katlama C, Herve P, Brivet F, Simonneau G, Duroux P, Regnier B (1986) Pentamidine and pancreatitis [letter]. Ann Intern Med 105: 140–141PubMedGoogle Scholar
  108. 108.
    Samuels BI, Culbert SJ, Okamura J et al. (1976) Early detection of chemotherapy-related pancreatic enlargement in children using abdominal sonography. A prehminary report. Cancer 38: 1515–1523PubMedCrossRefGoogle Scholar
  109. 109.
    Sanford KA, Mayle JE, Dean HA, Greenbaum DS (1988) Metronidazole-associated pancreatitis. Ann Intern Med 109: 756–757PubMedGoogle Scholar
  110. 110.
    Scarpelli DG (1989) Toxicology of the pancreas. Toxicol Appl Pharmacol 101 : 543–554PubMedCrossRefGoogle Scholar
  111. 111.
    Schmidt P, Friedman IS (1967) Adverse effects of ethacrynic acid. NY State J Med 67: 1438–1442Google Scholar
  112. 112.
    Schultz JC, Adamson JS, Workman WW, Norman TD (1963) Fatal liver disease after intravenous administration of tetracycline in high dosage. N Engl J Med 269: 999–1004PubMedCrossRefGoogle Scholar
  113. 113.
    Sgro C, Escousse A (1991) Side effects of fibrates (except liver and muscle). Thérapie 46: 351–354 (in French)PubMedGoogle Scholar
  114. 114.
    Siefkin AD (1980) Sulindac and pancreatitis (letter). Ann Intern Med 93: 932–933PubMedGoogle Scholar
  115. 115.
    Siemers RF, Friedenberg WR, Norfleet RG (1985) High-dose cytosine arabinoside-associated pancreatitis. Cancer 56: 1940–1942PubMedCrossRefGoogle Scholar
  116. 116.
    Steer ML (1989) Classification and pathogenesis of pancreatitis. Surg Clin North Am 69: 467–480PubMedGoogle Scholar
  117. 117.
    Steinberg WM, Lewis JH (1981) Steroidinduced pancreatitis: Does it really exist? Gastroenterology 81: 799–808PubMedGoogle Scholar
  118. 118.
    Stenvinkel P, Alvestand A (1988) Loop diuretic-induced pancreatitis with rechallenge in a patient with malignant hypertension and renal insufficiency. Acta Med Scand 224: 89–91PubMedCrossRefGoogle Scholar
  119. 119.
    Stewart DJ, Feun LG, Maor M, Leavens M, Burgess MA, Benjamin RS, Bodey GP Sr (1983) Weekly cisplatin during cranial irradiation for malignant melanoma metastatic to brain. J Neurooncol 1: 49–51PubMedGoogle Scholar
  120. 120.
    Strange P (1975) Furosemide-induced pancreatitis? Br Med J 1: 434CrossRefGoogle Scholar
  121. 121.
    Sturdevant RAL, Singleton JW, Deren JJ, Law DH, McCleery JL (1979) Azathioprine-related pancreatitis in patients with Crohn’s disease. Gastroenterology 77: 883–886PubMedGoogle Scholar
  122. 122.
    Suryapranata H, DeVries H (1986) Pancreatitis associated with sulphasalazine. Br Med J 292: 732CrossRefGoogle Scholar
  123. 123.
    Sussman S (1963) Severe salicylism and acute pancreatitis. Calif Med 99: 29–32PubMedGoogle Scholar
  124. 124.
    Teillet L, Chaussade S, Mory B, Roche H, Couturier D, Guerre J (1991) Pancréatite aiguë associée a une antibiothérapie par Perythromycine intraveneuse (letter). Gastroenterol Clin Biol 15: 265–266PubMedGoogle Scholar
  125. 125.
    Thomas FB, Falko JM, Caldwell JH, Mekhjian HS (1975) Effects of furosemide on pancreatic exocrine function. Gastroenterology 68: 998Google Scholar
  126. 126.
    Torosis J, Vender R (1987) Tetracycline-induced pancreatitis. J Clin Gastroenterol 9: 580–581PubMedCrossRefGoogle Scholar
  127. 127.
    Valentine FT, Seidlin M, Hochster H, Laverty M (1990) Phase I study of 2′, 3′-dideoxyinosine : experience with 19 patients at New York University Medical Center. Rev Infect Dis 12 (Suppl 5): S534–539PubMedCrossRefGoogle Scholar
  128. 128.
    Van der Heide H, ten Haaft MA (1981) Pancreatitis caused by methyldopa. Br Med J 282: 1930–1931CrossRefGoogle Scholar
  129. 129.
    Vermorken JB, Pinedo HM (1982) Gastrointestinal toxicity of cis-diammine dichloroplatinum. II. Personal observations. Neth J Med 25: 270–274PubMedGoogle Scholar
  130. 130.
    Villamil A, Hammer RA, Rodriguez FH (1991) Edematous pancreatitis associated with intravenous pentamidine. South Med J 84: 796–798PubMedCrossRefGoogle Scholar
  131. 131.
    Warren SE, Mitas JA, Swerdlin AHR (1980) Pancreatitis due to methyldopa: case report. Military Med 145: 399–400Google Scholar
  132. 132.
    Weetman RM, Baehner RL (1974) Latent onset of clinical pancreatitis in children receiving L-asparaginase therapy. Cancer 34: 780–785PubMedCrossRefGoogle Scholar
  133. 133.
    Wilkinson ML, O’Driscoll R, Kiernan TJ (1981) Cimetidine and pancreatitis. Lancet i: 610–611CrossRefGoogle Scholar
  134. 134.
    Wilson AE, Mehra SK, Gomersall CR (1967) Acute pancreatitis associated with furosemide therapy. Lancet 1: 1355Google Scholar
  135. 135.
    Wood G, Wetzig N, Hogan P, Whitby M (1991) Survival from pentamidine induced pancreatitis and diabetes mellitus. Aust NZJ Med 21: 341–342CrossRefGoogle Scholar
  136. 136.
    Yarchoan R, Pluda JM, Thomas RV, Mitsuya H, Brouwers P, Wyvill KM, Hartman N, Johns DG, Broder S (1990) Long-term toxicity/activity profile of 2′, 3′-dideoxyinosine in AIDS or AIDS-related complex. Lancet 336: 526–529PubMedCrossRefGoogle Scholar
  137. 137.
    Zion MM, Goldberg B, Suzman MM (1955) Corticotrophin and cortisone in the treatment of scleroderma. Q J Med 24: 215–217PubMedGoogle Scholar
  138. 138.
    Zuger A, Wolf BZ, el-Sadr W, Simberkoff MS, Rahal JJ (1986) Pentamidine-associated fatal acute pancreatitis. JAMA 256: 2383–2385PubMedCrossRefGoogle Scholar
  139. 139.
    Zygmunt DJ, Williams HJ, Bienz SR (1986) Acute pancreatitis associated with long-term sulindac therapy. West J Med 144: 461–462PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1993

Authors and Affiliations

  • C. B. Kölbel
    • 1
  • M. V. Singer
    • 1
  1. 1.Abteilung für Gastroenterologie, Medizinische KlinikUniversitätsklinikum EssenGermany

Personalised recommendations